Background: The herpes simplex virus (HSV) UL41 gene product, virion host shutoff (Vhs) protein, mediates the rapid degradation of both viral and cellular mRNA. This ability suggests that Vhs protein can be used as a suicide gene in cancer gene therapy applications. The recent reports have shown that the degradation of cellular mRNA during herpes simplex infection is selective. RNA containing A...

Retroviruses cause cancers in a variety of animals and humans. Research on retroviruses has provided important insights into mechanisms of oncogenesis in humans, including the discovery of viral oncogenes and cellular proto-oncogenes. The subject of this review is the mechanisms by which retroviruses that do not carry oncogenes (non-acute retroviruses) cause cancers. The common theme is that th...

The theory of behavioral communication for humanoid robots that in teract with humans is discussed in this paper For behavioral communication it is fundamental for a humanoid robot to recognize the meaning of the whole body mo tion of a human According to the previous works it can be done in the symbolic level by adopting the proto symbol space de ned by the Hidden Markov Models based on the mi...

This paper contrasts three different schemes of reference relevant to understanding systems of perceptual representation: a location-based system dubbed "feature-placing", a system of "visual indices" referring to things called "proto-objects", and the full sortal-based individuation allowed by a natural language. The first three sections summarize some of the key arguments (in Clark 2000) to t...

It has been shown that effective chiral hadronic models can satisfactorily describe nuclear matter, properties of finite nuclei as well as the structure of neutron stars1. While most of the approaches are based on variations of the linear sigma model or its non-linear realization, in the approach discussed here the scalar sigma meson serves to split the nucleon and its chiral partner (particle ...

Deep-sea hydrothermal vents are one of the most unique and fascinating ecosystems on Earth. Although phylogenetic diversity of vent communities has been extensively examined, their physiological diversity is poorly understood. In this study, a GeoChip-based, high-throughput metagenomics technology revealed dramatic differences in microbial metabolic functions in a newly grown protochimney (inne...

Abstract From a linguistic standpoint, Proto-Japonic and Proto-Koreanic are assumed to have split off the Transeurasian languages in southern Manchuria. The idea that came earlier than chronological scheme means language first entered Korean Peninsula, from there spread Japanese archipelago at beginning of Yayoi period, around ninth century BC, while arrival Korea is associated with rolled rim ...

Farrell Ackerman and John Moore, published by CSLI Publications. ©2001 by CSLI Publications. All rights reserved. This text may be used and shared in accordance with the fair-use provisions of U.S. copyright law, and it may be archived and redistributed in electronic form, provided that this entire notice, including copyright information, is carried and provided that CSLI Publications is notifi...

background & objective: the current approaches to reduce the risk of colorectal carcinoma are through the detection and removal of the precursor lesion” adenomatous polyps”. the study was conducted to evaluate the immunohistochemical expression of p53 and bcl2 in colorectal adenomas and carcinomas. patients and methods: a total of 86 cases, 33 colorectal adenomas, 33 colorectal adenocarcin...