Many connective tissue diseases are characterized by fatigue, which is described in the literature as prostration, weakness, lassitude or asthenia. In many other diseases (autoimmune, neurologic or metabolic) fatigue impinges on daily activities and thus influences the quality of life. Different molecular backgrounds are involved in the development of fatigue. Not only does the immunosuppressiv...

driver fatigue may impose the risk of crashes and is a leading cause of death in transportation industry. this study aimed to detect driver cognitive fatigue based on changes in eeg frequency bands in non-professional drivers during a simulated driving task. in a descriptive-analytical study, 12 healthy male car drivers took part in a two hour driving session on a simulated monotonous road, whi...

This paper deals with the improvement of fatigue life of AISI 1040 steel components by using a High Power Diode Laser (HPDL). First, the meaningfulness of each operational parameter was assessed by varying the experimental laser power and scan speed. After laser treatment, fatigue tests were performed to investigate the influence of laser processing parameters on the material resistance. The fa...

The goal of this research was to analyze the effects of fatigue on the shock waves generated by foot strike. Twenty-two subjects were instrumented with an externally attached, lightweight accelerometer placed over the tibial tuberosity. The subjects ran on a treadmill for 30 min at a speed near their anaerobic threshold. Fatigue was established when the end-tidal CO2 pressure decreased. The res...

Repetitive muscle contraction is associated with increased superoxide production in skeletal muscle. 1-8 There is considerable evidence that muscle fatigue during prolonged exercise is associated with oxidant stress in muscle fibers, and that this stress is indeed partially responsible for the fatigue. Thus, pharmacological strategies which depress the antioxidant defenses of muscle fibers acce...

One aspect of motor fatigue is the exercise-induced reduction of neural activity to voluntarily drive the muscle or muscle group. Functional magnetic resonance imaging provides access to investigate the neural activation on the whole brain level and studies observed changes of activation intensity after exercise-induced motor fatigue in the sensorimotor cortex. However, in human, little evidenc...

OBJECTIVE To examine the relationship of fatigue in people with rheumatoid arthritis (RA) with self-efficacy, positive and problematic aspects of social support, and demographic and disease-related variables. METHOD Out-patients with at least 5 yr RA were studied. Fatigue was measured with a visual analogue scale. Other variables included were: positive social support [Social Support List-Int...

OBJECTIVES Fatigue is a major cause of disability in primary Sjögren's syndrome (pSS). Fatigue has similarities with sickness behaviour in animals; the latter mediated by pro-inflammatory cytokines, in particular interleukin (IL)-1, acting on neuronal brain cells. We hypothesised that IL-1 inhibition might improve fatigue in pSS patients; thus, we examined the effects and safety of an IL-1 rece...

conclusions independent of their level, professional soccer players, need 48 hours to recover after an official match. professionals gain more fatigue than young players after a match, but recover as fast. thus, they recover more efficiently especially due to a better physical condition and fitness training. it is expected that the results showed in the study help elite soccer and fitness coach...