Background: Hirsutism is a common clinical problem that cause great distress to the patient, and which true incidence unknown. However, it more among Mediterranean women. excessive terminal hair growth in women androgen-dependent. Often of hyperandrogenism but can be also idiopathic. In hyperandrogenic states like cases PCOS, associate with other cutaneous signs this endocrine disorder acne AGA...

Minoxidil, an antihypertensive peripheral vasodilator, is a prodrug converted to an active metabolite which is potassium (K) channel opener, act by hyperpolarizing smooth muscles. Minoxidil in the treatment of androgenic alopecia has led to the hypothesis that other pathways could mediate this form of hair loss, including infection and/or micro-inflammation of the hair follicles. It stimulates ...

Androgenetic alopecia (AGA) is a hereditary, androgendependent dermatological disorder more common in men. It is occasionally seen in women. It commonly begins by 20 years of age and affects nearly 50% of men by the age of 50 years [1]. It is a progressive thinning of the scalp hair in a defined pattern causing significant lowering of the self esteem and psychological well being of the patient....

INTRODUCTION Hair loss or alopecia affects the majority of the population at some time in their life, and increasingly, sufferers are demanding treatment. Three main types of alopecia (androgenic [AGA], areata [AA] and chemotherapy-induced [CIA]) are very different, and have their own laboratory models and separate drug-discovery efforts. AREAS COVERED In this article, the authors review the ...

Mesenchymal stem cell (MSC)-based therapy involving both autologous and allogeneic MSCs shows great promise in treating several conditions. MSCs promote wound healing, and can differentiate into multiple cell lineages, including keratinocytes. Therefore, MSCs can be used for the treatment of congenital or acquired skin defects. Because of their immunomodulatory properties, MSCs may be useful fo...