AIM To study the effects of Boesenbergia rotunda (Krachai) on sexual behaviour in male albino rats. METHODS Thirty-two male Wistar rats were equally divided into four groups: experimental groups were gavaged with the ethanolic extract of the rhizome of B. rotunda at doses of 60, 120 and 240 mg/kg and a control group received distilled water, for 60 days. Sexual behaviour, reproductive organs,...

The objective: on the basis of a comprehensive examination women reproductive age to establish frequency phenotypes (clinical variants) polycystic ovary syndrome (PCOS).Materials and methods. 34 patients (main group) who complained menstrual disorders and/or dermatopathies by recommendation dermatologist were examined. control group is represented 30 without gynecological somatic pathology. mea...

Antibodies to native DNA and to polyadenylic acid (Poly A) occur spontaneously and undergo a regulated switch from IgM to IgG during the course of autoimmune disease in NZB/NZW F(1) (B/W) mice. B/W females have higher titers and earlier commitment to 7S antibodies to DNA and Poly A, whereas B/W males bind DNA and Poly A primarily by 19S antibodies. We have performed castration experiments to de...

T HE mechanism of sexual behavior has long been an intriguing although frustrating subject of investigation. With the discovery of the role of the gonads as producers of hormones, and particularly after the isolation, purification, and synthesis of the steroid hormones, biologists believed that a simple explanation of sexual behavior was at last available. Many observers had noted that sexual b...

Steroid hormones and castration have been suc cessfully employed in the palliative treatment of advanced mammary cancer (3, 8, 9,12,16,17, 24, 29-31, 35).* Complications may arise during this therapy, however, which necessitate special con sideration; one of the more serious of these is hypercalcemia. The progressive advanced stages of the syndrome are manifested by anorexia, nausea, vomiting, ...

We investigated the effect of long-term supraphysiologic doses of anabolic androgenic steroids (AAS) on atrial electromechanical delay (AEMD) in male bodybuilders. We clearly demonstrated that long-term consumption of supraphysiologic doses of AAS is associated with higher values of inter- and intra-AEMD in healthy young bodybuilders.

1. By using ultrasonic treatment in media of high ionic strength, the RNA polymerase activities associated with prostatic nuclei and nucleoli can be completely solubilized. Such enzyme preparations are entirely dependent on the provision of added DNA for full activity. 2. The solubilized enzymes from the nucleolar and extranucleolar regions can be separated by ion-exchange chromatography. 3. Ba...

  The Kor River (Fars province) was divided into three parts and water and fish specimens were collected monthly and the concentrations of four heavy metals were determined using the Induction Coupled Plasma Method. As middle sampling zone was the main entrance and discharges of industries into the River, the concentrations of heavy metals in tissue of fish from this zone were significantly hig...

Studies from this laboratory have shown that renal N-nitrosodimethylamine demethylase (NDMA demethylase), an enzyme responsible for the metabolism of NDMA, shows age- and sex-related differences and is modulated by testosterone. These results have been positively correlated with NDMA-induced mutagenicity and carcinogenicity studies; however, relatively large doses of testosterone (100 mg/kg or ...

Industrial and domestic sewage effluents have been found to cause reproductive disorders in wild fish, often as a result of the interference of compounds in the effluents with the endocrine system. This thesis describes laboratory-based exposure experiments and a field survey that were conducted with juveniles of the three-spined stickleback, Gasterosteus aculeatus. This small teleost is a comm...