Abstract
 Background and objective: Protective effect of (Andrographis Paniculata) on 4-Vinylcyclohexene Diepoxide.
 Material methods:A group 55 female albino rats undergo experiment the outcome 4-vinylcyclohexene Diepoxide injection for a priod two weeks, as well treatment methanolic leaf extract Andrographis paniculata oral administration four weeks. Injection concentrations (160 32...

Aqueous extract of Andrographis paniculata was examined for antioxidant activity using rat liver subcellular organelles as model systems. The study deals with two important biological oxidative agents, ascorbate-Fe(+2) and AAPH generating hydroxyl and peroxyl radical, respectively. Oxidative damage was examined against the inhibition of membrane peroxidation, protein oxidation and restoration i...

Andrographis paniculata, "King of bitters" is a popularly known medicinal plant extensively used in many parts of the world for treatment of various diseases. Since recent past, anaphylactic/allergic type adverse events were reported upon A. paniculata usage, the study aimed to evaluate the anaphylactic and anaphylactoid potential of A. paniculata extract and andrographolide (a major phytoactiv...

Andrographis paniculata (Burm.f.) Nees (Acanthaceae), a plant widely used as traditional herbal medicine in many countries, has drawn attention of the researchers in recent years. Its major constituents are diterpenoids and flavonoids. This article reviews the anti-hepatotoxic effects of A. paniculata extract and derivative compounds, such as andrographolide, the major active compound, most stu...

Andrographis lineata is an herbal medicinal plant used in traditional medicine as a substitute for Andrographis paniculata. Here, using mature leaf explants of A. lineata we demonstrate for the first time the callus induction established on MS medium containing 1.0 mg l-1 IAA. Dried callus was subjected to solvent extraction with acetone. Further the acetone residue was separated by silica gel ...

The cholinergic hypothesis of Alzheimer's disease (AD) has provided the rationale for the current pharmaco-therapy of this disease, in an attempt to reduce the cognitive decline caused by cholinergic deficits. Nevertheless, the search for potent and long-acting acetylcholinesterase (AChE) inhibitors that exert minimal side effects in AD patients is still ongoing. AChE inhibitors are currently t...

Medicinal plants are in prevalence from the origin of the earth which has been efficiently used by ancient people as a cure for various ailments. The plant extracts are identified and act as an important source of active ingredient and secondary metabolite products such as alkaloid, terpenoids, which is used in curing diseases, for drug production and perpetuating good health by both the tradit...

Guided by bioassay test results, we have isolated an active compound from the hexane layer of the extract of Andrographis paniculata and it was identified as 14-deoxyandrographolide. Although this compound has been known as a medicine in Pharmacology, its antifeedant activity against insects has never been reported yet. The minimum effective dose (MED = 100μg/leaf disc) on the isolated compound...