A number of previous reviews have very eloquently summarized pain models and endpoints in animals. Many of these reviews also discuss how animal models have enhanced our understanding of pain mechanisms and make forward-looking statements as to our proximity to the development of effective mechanism-based treatments. While a number of reports cite failures of animal pain models to predict effic...

Snakehead fish or Channa Striata is a type of freshwater that has high economic value in Indonesia. Aims this study was to evaluating the effect adding different protein sources snakehead feed on growth, blood glucose levels, and albumin content (Channa Striata). This consisted 3 treatments each given 6 replications. Treatment A: Use made from nilem flour. B: golden snail flour C: earthworm The...

To deepen understanding and hasten the development of treatments, cancer needs to be modelled more accurately in vitro; applying tissue-engineering concepts and approaches in this field could bridge the gap between two-dimensional studies and in vivo animal models.

They take some of the stress out of making decisions about using “alternative” ingredients in animal feeds. At least that is what they were originally designed to do. They may also be helpful for making conclusions about many other types of experiments and designing experiments for many other purposes species, cultivars, etc. The PTSD.xls workbooks simulate experiments with two treatments and w...

Abstract Comfort (Ralco Agriculture; Marshall, MN) is a feed additive that contains essential oils and capsicum which are antioxidants selectively antimicrobial. The objective of this study was to evaluate the influence on growth, intramuscular fat (IMF) accretion, ultrasound ribeye area (REAU) in Akaushi crossbred steers heifers at time weaning. Steers (body weight = 257 ± 26.8 kg; n 56) were ...

An eleven month old filly was referred to the Research and Teaching Hospital of the Faculty of Veterinary Medicine at the University of Tehran. The animal presented a three-week history of diarrhea and previous treatments had failed to effect a recovery. Based on the history, clinical findings and results of laboratory investigations, it was assumed that a gastrointestinal disorder was affectin...

The development of treatments for Ebola virus disease (EVD) has been hampered by the lack of small-animal models that mimick human disease. Here we show that mice with transplanted human hematopoetic stem cells reproduce features typical of EVD. Infection with Ebola virus was associated with viremia, cell damage, liver steatosis, signs of hemorrhage, and high lethality. Our study provides a sma...

Boric acid dust treatments were evaluated as a tool for the integrated management of the German cockroach, Blattella germanica (L.), in commercial confined swine production. The efficacy of boric acid dust was comparable to that of an organic residual insecticide, cyfluthrin, which is commonly used to control cockroaches in this environment. Fall treatments suppressed the cockroach population f...

AstraZeneca's Oncology in vivo data integration platform brings multidimensional data from animal model efficacy, pharmacokinetic and pharmacodynamic data to animal model profiling data and public in vivo studies. Using this platform, scientists can cluster model efficacy and model profiling data together, quickly identify responder profiles and correlate molecular characteristics to pharmacolo...

Despite recent advances in stroke prevention and acute stroke therapy, few treatments exist for reversal of fixed neurological deficits after stroke. Cellular therapy offers the possibility of improving neurological deficits months or even years after stroke. Animal studies provide evidence that such treatment may be effective. Many questions, however, remain unanswered regarding cellular thera...