BACKGROUND During IVF or ICSI cycles, ovarian hyperstimulation syndrome (OHSS) is a major problem. The aim of this prospective, multicentre, comparative study (using historical controls) was to assess the efficacy of a GnRH antagonist protocol in preventing OHSS in selected patients who had experienced OHSS or had been at risk of OHSS in their previous IVF/ICSI attempt. METHODS AND RESULTS Pa...

ObjectiveTo evaluate whether physicians’ choice of ovarian stimulation protocol is associated with laboratory outcomes.DesignRetrospective cohort study.SettingSingle academic center.Patient(s)The subjects were 4,458 patients who completed more than one in vitro fertilization cycle within 1 year. On second stimulation, 49% repeated the same and 51% underwent a different one.Intervention(s)Estrad...

Abstract Study question Could exogenous progestin replace the use of an antagonist GnRH (GNRH-antagonist) without any effects on embryo morphokinetics and implantation rate in freeze-all cycles? Summary answer Exogenous leads to slower development increased cyclés cancellation rate, with when compared cycles using GnRH-antagonist. What is known already Improvements cryopreservation techniques a...

•We used Random-Start for the IVF cycle in urgent settings of gynecological cancer.•Oocytes can be obtained at any time before cancer treatment efficiently.•Oocyte maturity rates were comparable with conventional antagonist protocol.•Random-Start protocol is promising in emergency fertility preservation.

OBJECTIVE To systematically evaluate the effectiveness of the gonadotropin-releasing hormone (GnRH) antagonist on in vitro fertilisation (IVF) in patients with polycystic ovary syndrome (PCOS). METHODS Nine types of databases were searched by computer, and nine types of relevant journals were searched manually. Randomized, controlled trials of the effects of the GnRH antagonist and GnRH agoni...