The peripheral blood absolute lymphocyte/monocyte count ratio at diagnosis (ALC/AMC-DX) predicts survival in classical Hodgkin lymphoma (cHL). However, a limitation of the ALC/AMC-DX is the inability to assess sequentially the host/tumor interaction during treatment. Therefore, we retrospectively examined the ALC/AMC ratio, as a surrogate marker of host immunity (ALC) and tumor microenvironment...

This paper extends analysis of the Adaptive Mixed Criticality (AMC) scheme for fixed-priority preemptive scheduling of mixed-criticality systems to include tasks with arbitrary deadlines. Both of the previously published schedulability tests, AMC-rtb and AMC-max are extended to cater for tasks with deadlines that may be greater than their periods. Evaluations show that the simpler method, AMC-r...

The advent of novel therapies has significantly changed the therapeutic landscape in multiple myeloma (MM). However, MM remains largely incurable and patients undergo disease relapse frequently after a short remission period. This is partly because MM is characterized by the loss of critical mediators of immune surveillance and the development of an immunologic milieu that fosters both disease ...

Adaptive Modulation and Coding (AMC) is combined with Multiple Input Multiple Output (MIMO) multiplexing to improve the throughput performance of AMC. In addition, Selection Transmit Diversity (STD) is considered in MIMO multiplexing to achieve higher diversity gain. AMC-STD-MIMO multiplexing system is proposed. STD in our simulation selects 2 transmission antennas from 4 antennas and AMC-MIMO ...

Mandibular hypomobility results from various disorders affecting the stomatognathic system. Arthrogryposis multiplex congenita (AMC) is an uncommon systemic disorder with mandibular hypomobility involved. Notably few cases of AMC with limited mouth opening and reduced range of jaw movement have been described in which this restriction has been attributed to involvement of the coronoid process. ...

Although the proteasome plays a critical role in the controlled degradation of proteins involved in cell cycle control, the direct modulation of proteasomal function by growth regulatory signaling has not yet been demonstrated. We assessed the effect of transforming growth factor (TGF)-beta, a potent inhibitor of cell growth, on proteasomal function. TGF-beta selectively decreased hydrolysis of...

BACKGROUND To evaluate the knowledge, attitudes and beliefs about adult male circumcision (AMC), assess the association of AMC with HIV incidence and prevalence, and estimate AMC uptake in a Southern African community. METHODS A cross-sectional biomedical survey (ANRS-12126) conducted in 2007-2008 among a random sample of 1198 men aged 15 to 49 from Orange Farm (South Africa). Face-to-face in...

The current research aims to further investigate the application of Automated Machine Control/Guidance (AMC/G) in construction projects and proposes an integrated approach for: (1) Improving the administrative infrastructure required for the optimal application of AMC/G; and (2) Orchestrating the machine-level AMC/G technologies into a coherent project-level system committed to the coordination...

BACKGROUND The prognostic significance of the circulating absolute monocyte count (AMC) in patients with locally advanced hepatocellular carcinoma (HCC) is uncertain. This study was designed to assess the association of circulating AMC with survival outcomes in patients diagnosed with locally advanced or metastatic HCC receiving systemic chemotherapy. MATERIALS AND METHODS Between January 1, ...