Obstructive and nonobstructive forms of hydronephrosis (increased diameter of the renal pelvis and calyces) and hydroureter (dilatation of the ureter) are the most frequently detected antenatal abnormalities, yet the underlying molecular mechanisms are largely undefined. Hedgehog (Hh) proteins control tissue patterning and cell differentiation by promoting GLI-dependent transcriptional activati...

Introduction Duplications of the ureter represent one of the most common anomalies of the urinary tract. Duplications may be complete or incomplete and can be associated with functioning renal moieties with orifices that open into the bladder. Duplications are often completely asymptomatic and often come to light only in the course of investigations for other reasons. Clinical problems are the ...

Duplex kidney is one of common major congenital abnormalities of the urinary tract with an incidence about 1% of all live births and higher frequency in females than in males. Majority of duplex kidneys are unilateral. Although the antenatal diagnosis of fetal hydronephrosis is simple, the diagnosis of fetal renal duplication is infrequent, especially in case the collecting system is not dilate...

Background & Aims: Hydronephrosis is a common problem in prenatal and newborn infants diagnosed by ultrasonography. Bladder to ureter reflux, the upper or lower urinary tract obstruction, and neurogenic bladder are the most common causes of hydronephrosis in newborns and infants. Methods: In this study, 100 neonates and infants with hydronephrosis were observed clinically and laboratorically fo...

INTRODUCTION AND AIM Antenatal treatment of obstructive uropathy, although widely performed, remains controversial. This study evaluated the long-term outcome of managing patients with posterior urethral valves (PUV), highlighting the effect of antenatal vesicoamniotic shunt placement for patients who underwent fetal surgery. METHODS The medical records of 58 patients with PUV were retrospect...

OBJECTIVE To assess whether antenatal health care consumption is associated with maternal body mass index (BMI). DESIGN A register based observational study. METHODS The Swedish Medical Birth Register, the Maternal Health Care Register, and the Inpatient Register were used to determine antenatal health care consumption according to BMI categories for primiparous women with singleton pregnan...