Curcumin (diferuloylmethane) is a polyphenol responsible for the yellow color of the curry spice turmeric. It has been used in a variety of diseases in traditional medicine. Modern scientific research has demonstrated its anti-inflammatory, anti-oxidant, anti-carcinogenic, anti-thrombotic, and cardiovascular protective effects. In this review, we focused mainly on the effects of curcumin on the...

Inhalation of asbestos fibers is associated with high incidence of lung cancers and pleural or peritoneal mesotheliomas in humans. All of these lesions were successfully reproduced in animal experiment, and it was shown that asbestos neoplasm may occur with or without accompanying asbestosis. Incidence of tumors from crocidolite was nearly three times as high as from chrysotile or amosite. It i...

Turmeric is the rhizomatous, herbaceous, perineal plant having many traditional and medicinal uses. Traditionally turmeric was used for spices in food system of medicine as like Ayurvedic medicine, Siddha Unani Chinese System purpose anti-microbial, antiseptic, anti-oxidant mild digestive problems.Turmeric consists wide variety phytochemicals such Demethoxycurcumin (DMC), Bis-Demethoxycurcumin ...

BACKGROUND Arachidonic acid metabolite, generated by cyclooxygenase (COX), is implicated in the colorectal cancer (CRC) pathogenesis. Inhibiting COX may therefore have anti-carcinogenic effects. Results from use of non-steroidal anti-inflammatory drugs inhibiting only COX have been conflicting. It has been postulated that this might result from the shunting of arachidonic acid metabolism to the...

Isothiocyanates are naturally occurring small molecules that are formed from glucosinolate precursors of cruciferous vegetables. Many isothiocyanates, both natural and synthetic, display anti-carcinogenic activity because they reduce activation of carcinogens and increase their detoxification. This minireview summarizes the current knowledge on isothiocyanates and focuses on their role as poten...

Indole-3-carbinol (I3C) is a naturally occurring substance that shows anti-carcinogenic properties in animal models. Besides its clear anti-carcinogenic effects, some studies indicate that I3C may sometimes act as a tumor promoter. Indolo[3,2-b]carbazole (ICZ), which is formed in the acidic environment of the stomach after intake of I3C, has a similar structure to, and shares biological effects...

Prefatory Note National Institute of Health and Nutrition as a brain of dietitians in Japan........................Eiji Oshino CURRENT RESEARCH PROJECTS Investigation of a new biological function of nutrient: Vitamin D........ ........................Jun Yamauchi THOUGHTS ON HEALTH AND NUTRITION RESEARCH About “Dietary Survey”... ....................................................................