how to cite this article: hashemiaghdam a, sharifi a, miri m, tafakhori a. seizure-control effect of levatiracetam on juvenile myoclonic epilepsy and other epileptic syndromes: literature review of recent studies. iran j child neurol. spring 2015;9(2):1-8. abstract objective various epileptic syndromes may present in adolescence and juvenile myoclonic epilepsy (jme) is known to be the most comm...

Epilepsy is one of the most common neurological disorders in dogs and is treated by chronic administration of antiepileptic drugs (AEDs). In human beings with epilepsy, it is common clinical practice to consider drug withdrawal after a patient has been in remission (seizure free) for three or more years, but withdrawal is associated with the risk of relapse. In the present study, the consequenc...

Epileptic seizures are a common and clinically relevant problem in paediatric oncology. Attributable to the heterogeneity of this group of patients and a number of possible comorbidities antiepileptic treatment in paediatric oncology poses a number of diagnostic and therapeutic challenges. This requires a close interdisciplinary approach to the seizing child or adolescent. A prompt and detailed...

OBJECTIVE Adequate control of intractable epilepsy continues to be a challenge. Little is known about the role of VNS therapy in intractable epilepsy in patients who failed to respond to surgical management. The objective of the present study is to determine the efficacy of vagus nerve stimulation therapy in patients with intractable epilepsy who have failed surgical and medical therapy. METH...

Background: Epilepsy is the commonest chronic and highly stigmatized neurological problem that affects many children. It defined by two or more unprovoked seizures. The main stay of epilepsy management anti-epileptic drugs strict adherence to key successful treatment. 70% children will become seizure free with appropriate drug (AED) goal treatment includes minimizing risk recurrent seizures sid...

Epidemiologic data on convulsive status epilepticus (CSE) is needed to develop preventative strategies. Epilepsy is one of the known risk factors for CSE. A systematic review of epidemiologic studies on status epilepticus (SE) completed in the United States and Europe reports that people with epilepsy account for less than 50% of cases of SE in all age groups. Less is known about the epidemiolo...

Epilepsy is a chronic disease affects CNS in various ages. WHO estimates 50 million people are suffering from epilepsy worldwide which make it a serious prevalent problem among neurological diseases. Intractable epilepsy (IE) affects about 20-30% of epileptic patients who failed to be seizure - free after antiepileptic drug (AED) consumption. Although many AEDs now are available for epilepsy tr...

M e t h o d s Design: Randomized controlled trial. Allocation: Concealed.* Blinding: Unblinded.* Follow-up period: 2 and 5 years. Setting: Centers in the United Kingdom, India, Chile, Hungary, Italy, the Netherlands, Poland, Portugal, Slovakia, and Yugoslavia. Patients: 1443 patients ≥ 1 month of age (mean age 25 y, 57% men) with documented history of ≥ 1 clinically definite, spontaneous, unpro...

OBJECTIVE This study was aimed at correlating the salivary and serum free concentrations of anti-epileptic drugs (carbamazepine, phenytoin and sodium valproate) in a population of neurological patients in a routine clinical setting. METHOD Twenty-seven paired serum/saliva specimens from 22 patients: 10 for carbamazepine, 8 for phenytoin and 9 for sodium valproate were obtained to study these ...

Oxidative stress has been suggested as a consequence and as a cause of epileptic seizures. Researches indicate Achillea wilhelmsii (A.wilhelmsii) has anti-oxidant and anti-spasmic effects on central nervous system. This plant grows in most part of Iran. An Iranian research that done in 2013 showed that the hydroalcoholic extract of Achillea wilhelmsii possesses an antioxidant effect in the brai...