A safe and effective vaccine against HIV is a global health priority. Large-scale phase III clinical vaccine trials based on neutralizing antibodies and cytotoxic T-lymphocytes have failed to provide protection, highlighting the lack of understanding of basic immune correlates of protection against HIV. The partial success of the RV144 vaccine trial, however, sparked an intense research effort ...

Human natural killer T (NKT) cells are characterized by their expression of an invariant T cell antigen receptor α chain variable region encoded by a Vα24Jα18 rearrangement. These NKT cells recognize α-galactosylceramide (α-GalCer) in conjunction with the MHC class I-like CD1d molecule and bridge the innate and acquired immune systems to mediate efficient and augmented immune responses. A prime...

An old question of T. Jech and K. Prikry asks if an existence of a precipitous ideal implies necessary existence of a normal precipitous ideal. The aim of the paper is to prove some results in the positive direction. Thus, it is shown that under some mild assumptions, an existence of a precipitous ideal over א1 implies an existence of a normal precipitous ideal over א1 once a Cohen subset is ad...

Employing the thermodynamic geometry approach, we explore phase transition of four dimensional spinning black holes in an anti-de Sitter (AdS) spaces and found following novel results. (i) Contrary to charged AdS hole, curvature hole diverges at critical point, without needing normalization.(ii) There is a certain region with small entropy space parameters for which positive repulsive interacti...

the rings considered in this article are commutative with identity $1neq 0$. by a proper ideal of a ring $r$,  we mean an ideal $i$ of $r$ such that $ineq r$.  we say that a proper ideal $i$ of a ring $r$ is a  maximal non-prime ideal if $i$ is not a prime ideal of $r$ but any proper ideal $a$ of $r$ with $ isubseteq a$ and $ineq a$ is a prime ideal. that is, among all the proper ideals of $r$,...

Torsion theories are here extended to categories equipped with an ideal of 'null morphisms', or equivalently a full subcategory of 'null objects'. Instances of this extension include closure operators viewed as generalised torsion theories in a 'category of pairs', and factorization systems viewed as torsion theories in a category of morphisms. The first point has essentially been treated in [15].

The issues inherent in caring for an ever-increasing aged population has been the subject of endless debate and continues to be a hot topic for political discussion. The use of hospital-based facilities for the monitoring of chronic physiological conditions is expensive and ties up key healthcare professionals. The introduction of wireless sensor devices as part of a Wireless Body Area Network ...