نتایج جستجو برای: antigen presenting cells

تعداد نتایج: 1615635  

Journal: :Journal of virology 2013
Cleo Goyvaerts Jozef Dingemans Kurt De Groeve Carlo Heirman Ellen Van Gulck Guido Vanham Patrick De Baetselier Kris Thielemans Geert Raes Karine Breckpot

Antigen-presenting cells are a heterogeneous group of cells that are characterized by their functional specialization. Consequently, targeting specific antigen-presenting cell subsets offers opportunities to induce distinct T cell responses. Here we report on the generation and use of nanobodies (Nbs) to target lentivectors specifically to human lymph node-resident myeloid dendritic cells, demo...

Journal: :Journal of Immunology 2023

Abstract Promising cytotoxic (CD8 +) T cell-based cancer therapies have invigorated recent efforts to develop highly tunable, robust, and cost-effective artificial antigen presenting cells (aAPCs) for cell stimulation both ex vivoand in vivo. Natural APCs, such as dendritic (DCs), can be licensed deliver optimal activation signals (peptide-MHC S1, costimulatory S2, cytokine S3) CD8 +T with CD4 ...

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