ferula foetida (bunge) regel. is one of the most widespread and important ferula species with nutritional and medicinal applications. some phytochemicals with helpful cardiovascular effects have been isolated from ferula species. the present study was designed to evaluate the effects of hydroalcoholic extract of the stems of f. foetida in dexamethasone (dex)-induced hypertension in rats. hypert...

Cerebrovascular disease is one of the most common pathologies in practice a neurologist. Vascular cognitive impairment earliest and objective sign cerebrovascular pathology. The correction vascular risk factors – antihypertensive, antiplatelet, lipid-lowering therapy, have leading role treatment patients with diseases. It necessary to pay special attention non-drug methods such as quitting smok...

Angiotensin converting enzyme (ACE) catalyses the conversion of angiotensin I (Ang I) to angiotensin II (Ang II). The ACE activity directly related to hypertension as Ang II is the blood pressure regulating hormone. Therefore, ACE inhibitors are a major class of antihypertensive drugs. Captopril, chemical name, was the first orally active ACE inhibitory antihypertensive drug, discovered in 1977...

Angiotensin I-converting enzyme (ACE)-inhibitory peptides from the thermolysin digest of chicken muscle and the peptic digest of ovalbumin were isolated. However, some of them failed to show antihypertensive activity in spontaneously hypertensive rats (SHR). To clarify this discrepancy, ACE-inhibitory peptides from various sources were preincubated with ACE before measurement of ACE-inhibitory ...

Background: Antihypertensive plants are one of the means of hypertension control. Objective: To examine the clinical antihypertensive efficacy and safety of the plants found in Iran. Methods: PUBMED, MEDLINE, SCOPUS, EMBASE, SCIENCEDIRECT, PROQUEST, OVID, EBSCO, GOOGLE, and GOOGLE SCHOLAR were searched. The PRISMA guideline was observed. The search terms were Iran, Iranian, plant, herb, antihyp...

Previous studies have demonstrated that antihypertensive treatment resets baroreflex control of heart rate (HR) and increases cardiac vagal baroreflex sensitivity. However, it is uncertain whether baroreflex control of muscle sympathetic nerve activity (MSNA) also resets after treatment. We tested the hypothesis that chronic antihypertensive therapy alters baroreflex regulation of MSNA in patie...