objective: this study was planned to investigate whethercoriandrum sativum (c. sativum) is capable of protecting neurons against glucose/serum deprivation (gsd)-induced cytotoxicity. material and methods: the pc12 cells were cultivated for 24 h in standard media (high-glucose dmem containing fetal bovine serum) or for 6 h in gsd condition (glucose-free dmem, without serum) in the absence or pre...

background: in the present study, blood serum level of metals were determined in malarial pa­tients and compared with those in the normal subjects without complication using atomic absorp­tion spectrometer. methods: for the determination of these metals twelve intravenous blood samples each from re­ferred malarial patients and a group of normal subjects were collected and immediately centri­fug...

advanced glycation end-products (ages) are formed by non-enzymatic reaction between reducing sugar and protein. ages play important roles in pathogenesis of diabetic, aging complications, endothelial dysfunction and neurological diseases such as the alzheimer’s disease. therefore compounds that prevent the glycation reaction are purported to have therapeutic effect on patients with diabetes and...

serum fatty acids on 30 healthy lranian women were detemined by a gas chromatographic method. oleic and stearic acids were used as standards. the mean values were myristic acid 5. 7% , palmitic acid 43% , palmitoleic acid 5.3% , stearic acid 8% , oleic acid 21. 3% and linleic acid 16.4% of total fatty acid serum contents.

Mononuclear phagocytes and MHC class II+ dendritic cells (DC) were identified in frozen sections of skeletal muscle using a panel of pan-specific antimacrophage (MOMA-2, SER-4, Mac-1, F4/80), anti-major histocompatibility complex (MHC) class II (M5/114) and anti-DC (NLDC-145, N418, M342) monoclonal antibodies. Uninjured and regenerating skeletal muscle were investigated in SJL/J and BALB/c mice...

brucellosis is an endemic disease in our country. neurobrucellosis occurs in 5 to 10% of cases, and can present at any stage of of the disease. this study was undertaken to evaluate clinical, epidemiological and paraclinical aspects of brucellosis with and without neurological manifestations. data of 30 patients, 15 cases with nervous system involvement (neurobrucellosis) and 15 cases without n...

the bulk of our knowledge on immunosuppression in malnutrition comes from the experiments done on cell-mediated immunity. however, malnutrition-induced modifications of humoral immunity have been less understood. the objective of this study was to determine the effects of acute protein-energy malnutrition on serum levels of immunoglobulins and their subclasses in murine models. male and female ...

backgrounds and aims: thyroid hormones have a crucial physiological role to maintain balance of metabolism of body. thyroid hormones have an important role in metabolism and proliferation of blood cells. thyroid gland also has a vital influence on erythropoiesis by induction of erythropoietin secretion and proliferation of erythroid progenitors. in the present study, it was tried to evaluate th...

background and aims. oral lichen planus (olp) is an immunologic disorder. a large number of studies have reported that lipid rafts have a key role in receptor signaling of lymphocytes. here, we explore the potential of lipid rafts as targets for the development of a new class of agents to down-modulate immune responses and treat autoimmune diseases. materials and methods. the present cross-sect...

conclusions diabetes may be caused by toxoplasma gondii. presence of t. gondii in the pancreas at the same time could directly undermines the pancreas cells. when β cells are destroyed, insulin secretion would then be affected. probably the destruction of t. gondii affects nervous system and damages pancreatic cells leading to increased risk of diabetes. results the prevalence of igg antibodies...