AB-e-Boshghabi with scientific name of Centella asiatica is among those plants that has valid distribution only in the protection zone of Anzali lagoon. This herb has some active constituents, which categorizes it as a medicinal plant. This herb has been used as an anticancer, antifertility agent, antipsoriatic, an agent for wound healing, etc. This study was designed to identify collection, di...

The hybrid system based on nanoparticles (NPs) self-assembled by the conjugations of hyaluronic acid with cholesterol (HA-Chol NPs) combined with nicotinamide (NIC) for tacrolimus (FK506), ie, FK506 NPs-NIC, has been confirmed to exhibit a significant synergistic effect on FK506 permeation through and into intact skin; thus, it may be a promising approach for FK506 to effectively treat skin dis...

Tioxolone possess antipsoriatic and antibacterial properties. Therefore, it has been used in treating various skin and scalp disorders for many years. Spectroscopic analysis of tioxolone was presented by using density functional theory (DFT) calculations and experiments (FT-IR, FT-Raman and UVeVis). Molecular geometry and vibrational wavenumbers of tioxolone were investigated by using B3LYP met...

Recent studies have demonstrated that orally administered thiazolidinedione ligands of the peroxisome proliferator-activated receptor-gamma can ameliorate clinical features of psoriasis in humans. Thiazolidinediones also inhibit the proliferation of psoriatic keratinocytes in monolayer and organ culture, and at least one of these agents (troglitazone) inhibits epidermal hyperplasia of human pso...

The skin is the only tissue yet known in which the complete ultraviolet-B (UV-B)-induced pathway from 7-dehydrocholesterol to hormonally active calcitriol (1alpha,25-dihydroxyvitamin D(3)) occurs under physiological conditions. Epidermal synthesis of calcitriol could be of fundamental relevance because calcitriol regulates important cellular functions in keratinocytes and immunocompetent cells....

To prepare an herbal ointment using ethanolic extract of Berberis aristata and assess the anti-psoriatic effectiveness finished product. We were able to make multiple ointments that each categorized as F-1, F-2, F-3 by adding varying concentrations stearic acid cetyl alcohol learning about various formulation types, such oil in water. The analysis many factors, including pH, viscosity, spreadab...

OBJECTIVE To evaluate the role of biologic agents as antipsoriatic therapy. SUMMARY Mild psoriasis can generally be managed with topical therapy. Moderate-to-severe psoriasis has traditionally been treated with systemic therapies such as cyclosporine, methotrexate, retinoids, and phototherapy (ultraviolet B, psoralen plus ultraviolet A). The treatments for moderate-to-severe psoriasis often d...