نتایج جستجو برای: antisolvent

تعداد نتایج: 420  

Journal: :Organic Process Research & Development 2021

Choosing a solvent and an antisolvent for new crystallization process is challenging due to the sheer number of possible mixtures impact composition temperature on performance. To facilitate this choice, we present general computer aided mixture/blend design (CAMbD) formulation optimal pharmaceutical products. The proposed methodology enables simultaneous identification temperature, solvent, an...

Journal: :Separations 2022

Apigenin (API) has many biological activities, but its poor solubility limits clinical application. In this research, API nanoparticles were prepared by the liquid antisolvent precipitation (LAP) technique, which effectively improved and bioavailability of API. Through design a single-factor test, effects type dosage surfactants, concentration, to solvent volume ratio, speed time stirring, temp...

2016
Javad Shamsi Ahmed L. Abdelhady Sara Accornero Milena Arciniegas Luca Goldoni Ajay Ram Srimath Kandada Annamaria Petrozza Liberato Manna

We report chemical routes for the synthesis of both nanocrystals and bulk crystals of methylammonium (MA) lead halide perovskites employing N-methylformamide (NMF) as a source of MA ions. Colloidal nanocrystals were prepared by a transamidation reaction between NMF and an alkyl amine (oleylamine). The nanocrystals showed photoluminescence quantum yields reaching 74% for MAPbBr3 and 60% for MAPb...

Journal: :Journal of pharmaceutical sciences 2010
Gunilla B Jacobson Rajesh Shinde Rebecca L McCullough Nicholas J Cheng Adam Creasman Amanuel Beyene Robyn P Hickerson Can Quan Charlotta Turner Roger L Kaspar Christopher H Contag Richard N Zare

Many pharmaceuticals are formulated as powders to aid drug delivery. A major problem is how to produce powders having high purity, controlled morphology, and retained bioactivity. We demonstrate the use of supercritical carbon dioxide as an antisolvent for meeting this need for two model drug systems, quercetin, a sparingly soluble antioxidant, and short interfering RNA (siRNA), which can silen...

Journal: :National Science Review 2023

Abstract High-quality tin oxide electron transport layer (ETL) is a key common factor to achieve high-performance perovskite solar cells (PSCs). However, the conventional annealing technique prepare high-quality ETLs by continuous heating under near-equilibrium conditions requires high temperature and long fabrication time. Alternatively, we present non-equilibrium, photoexcitation-induced pass...

2011
Mahshid Kalani Robiah Yunus

The review focuses on the application of supercritical fluids as antisolvents in the pharmaceutical field and demonstrates the supercritical antisolvent method in the use of drug encapsulation. The main factors for choosing the solvent and biodegradable polymer to produce fine particles to ensure effective drug delivery are emphasized and the effect of polymer structure on drug encapsulation is...

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