Cryptorchidism has been on the rise for several decades and can be observed with frequency of 1-2% of males within the first year of age. It may appear as an isolated disorder or can be a consequence of genetic and endocrine abnormalities connected with somatic anomalies. Its genetic background still seems to be unclear although a range of genes can be responsible for the development of this sy...

Etiologycaly, possible causes of subfertility or infertility in men are poorly defined, but one important category may be elevated level of antisperm antibodies (ASA) caused by infective and/or auto-immune diseases of male reproductive system. In this study, blood sera from 45 infertile men of different age with ASA positive ELISA test were examined for the serum level of ASA before and after t...

vasectomy is one of the extensively used methods of contraception in family planning programs. antisperm antibodies (asa) develop after vasectomy which can result in auto-immune male infertility. the precise sperm antigens involved in the autoimmune response are still poorly defined, therefore we determined the circulating asa and identified relevant sperm antigens based on localization of bind...

We have successfully applied SDS (sodium dodecyl sulfate) gel/protein blot radioimmunobinding method to identify the molecular size of sperm antigens that elicit antisperm antibodies from patients with unexplained infertility. Following the transfer of renatured proteins from SDS gel of human sperm extract onto nitrocellulose strips, the radioimmunobinding was performed by incubating the strips...