Antithyroid drugs are widely used to treat hyperthyroidism, especially Graves' disease, but they tend to cause agranulocytosis, which increases the mortality rate. Granulocyte colony-stimulating factor decreases the duration of recovery from agranulocytosis. We retrospectively studied cases of antithyroid drug-induced agranulocytosis over the past 10 years in a northern Taiwan medical center. A...

BACKGROUND Graves' disease is a unique conglomeration of cardiovascular, neurological, ophthalmological, and other systemic manifestations. In this study we have tried to explore the psychiatric dimensions of this disease. AIMS This study attempted to explore clinical features, types, and treatment outcome of psychiatric disturbances in Graves disease. STUDY DESIGN This is a purposive study...

SUMMARY Thyroid storm is a rare and potentially life-threatening medical emergency. We experienced a case of thyroid storm associated with sepsis caused by pneumonia, which had a catastrophic course including recurrent cardiac arrest and subsequent multiple organ failure (MOF). A 22-year-old female patient with a 10-year history of Graves' disease was transferred to our emergency department (ED...

In 19-26% of patients hospitalized with suspected stroke, the cause neurological symptoms are not cerebrovascular diseases. this case newly diagnosed thyrotoxic periodic paralysis we presented clinical, laboratory and instrumental features disease. The search for allowed to identify an endocrinological disease - diffuse toxic goiter, prescribe antithyroid therapy. data prospective patient obser...

Risks to mother, fetus and neonate from untreated Graves' hyperthyroidism during gestation are compelling reasons for recommending pre-conception counselling. Pre-conception counselling should include discussion as to the optimum treatment of Graves' hyperthyroidism in women wishing to become pregnant. Thyrotropin receptor antibodies remain elevated following radioiodine therapy, so medical or ...

In order to evaluate the effect of treatment for hyperthyroidism based on a proposed criteria from our institution, the patients with the disease first seen at the Ito Hosiptal during 1965 were studied on the basis of clinical diagnosis and the follow-up study in 4-5 year period. Surgery was recommeded in the younger ages and radioiodotherapy in the higher ages for both sexes, though there was ...

Hashimoto’s encephalopathy (HE) is a rare disorder first characterized by Brain et al. in 1966 [1]. With only a few hundred reported cases, its etiology is not entirely understood but is believed to be related to the autoimmune mechanism of Hashimoto’s thyroiditis. Generally, patients diagnosed with HE demonstrate a progressive encephalopathy in the setting of elevated antithyroid antibodies. T...

BACKGROUND The main clinical manifestations of autoimmune thyroid diseases are Graves' disease (GD) and Hashimoto's thyroiditis (HT). Graves' disease is the cause of most cases of hyperthyroidism in childhood. Indications for radical therapy (surgery or 131I treatment) in children are still a matter of discussion, as sustained (sometimes very long) remission of GD is possible, while the radical...

Background It is well known that patients with severe neutropenia are susceptible to bacterial infections, which may become lifethreatening. This hematologic disorder frequently occurs as an adverse effect of certain drug therapies. One of them, currently encountered in practice, is therapy with antithyroid drugs. An infective source is identified in average in 20-30% of febrile neutropenia epi...