The localization and transporting properties of a kidney protein homologous to human erythrocyte protein CHIP28 was evaluated. The cDNA encoding rat kidney protein CHIP28k was isolated from a rat renal cortex cDNA library. A 2.8-kb cDNA was identified which contained an 807 bp open reading frame encoding a 28.8 kD protein with 94% amino acid identity to CHIP28. in vitro translation of CHIP28k c...

Dens invaginatus is a developmental anomaly, caused by deepening of the enamel organ into the dental papilla before calcification of the dental tissues. Teeth with dens invagination are susceptible to early caries and pulp necrosis within a few years of eruption or even before root end closure. This article reports two immature maxillary central incisors with type I and III dens invaginatus whi...

Derived from neural crests, the mature pulp is due to the proliferation and condensation of apical cells implicated in root lengthening. Adult cells are bound together by intercellular junctions (desmosomes and gap junctions), forming a network. They are further transported to the crown. Root lengthening is associated to tooth eruption and to vertical sliding. Composed by type I and III collage...