conclusions this method could be feasibly used for purification of large quantities of allicin from garlic extract. results semi-preparative hplc yielded a distinct peak with a retention time of 12.28 minutes. the purity (≥ 95%) and biological activity (p > 0.05) of purified allicin were comparable to the standard allicin. purified allicin produced same peak areas compared to the standard allic...

Oxidative damage by free radicals has been implicated in the pathogenesis of vascular disease in diabetes and hypertension. In the present study, the total antioxidant status in diabetic and hypertensive rats before and after treatment with garlic (Allium sativum) was determined. The total serum antioxidants were measured by a modified method reported earlier by Miller and coworkers. The reprod...

The effect of aqueous extract of garlic (GA) and Spondias mombin (SM) on the clastogenicity and hepatotoxicity of sodium arsenite (SA) was evaluated in Wistar rat using bone marrow micronucleus assay and monitoring the activities of -gamma transferase (γ-GT), alkaline phosphate (ALP), aspartate aminotransferase (AST), and alanine aminotransferase (ALT) in the plasma. 100 mg/kg b.w. of aqueous e...

Introduction: Garlic (Allium sativum, Family: Amaryllidaceae) is a seasoning plant cultivated all over the world. contains lot of bioactive compounds including organosulfur compounds, saponins, phenolic and polysaccharides. Anticoagulant activity one pharmacological properties Garlic. The aim this study was to review mechanism anticoagulant garlic summarise potential evidence about from past st...

In Ethiopia, honey produced by T. iridipennis in combination with garlic is widely used for traditional treatment of different infections. The objective of this study was to evaluate the synergic antibacterial effect of T. iridipennis honey and garlic mixture against standard and clinical pathogenic bacteria. The antimicrobial activity of garlic extract, tenegn honey and mixture of tenegn honey...

Garlic is known as a potent spice and a medicinal herb with broad therapeutic properties ranging from antibacterial to anticancer and anticoagulant. Our previous studies have shown some immunoregulatory effects for aged garlic extract, suggesting a key role for 14-kD glycoprotein of garlic in shifting the cytokine pattern to T helper-1. In present study, we investigated the effect of 1, 2, and ...

OBJECTIVE Garlic is a plant has been used as a flavor, and anti-microbial and anti-diarrheal agent. Infectious bronchitis virus (IBV) is a coronavirus. The available vaccines against IBV cannot cover new variants. This study evaluated the inhibitory effects of garlic extract on IBV. MATERIALS AND METHODS The constituents of garlic extract were detected by gas chromatography. This study was do...

Garlic has the charisma of a potent remedy and holds its repute of a therapeutic panacea since the dawn of civilization. An integrated approach was adopted to evaluate the genetic diversity among Chinese garlic cultivars for their antifungal potency as well as allicin content distribution and, furthermore; a bioassay was performed to study the bio-stimulation mechanism of aqueous garlic extract...