Increase in prevalence of cancer cases has been associated with the expansion of industrial, chemical and radioactive pollutants, also the gap between human being and nature (Colditz and Wei, 2012; Fasinu and Orisakwe, 2013). Despite the progress in the field of medicinal chemistry and development in the synthesis of several new therapeutic compounds, the role of plants and phytochemicals can n...

Background: Leishmaniasis is a parasitic disease that occurs in subtropical and tropical regions with approximately 350 million people worldwide 2 new cases annually. The annual increase cutaneous leishmaniasis (CL) observed, especially endemic areas such as Iran. Since there no effective vaccine, the detection of natural anti-leishmanial products essential. Objective: purpose this study was to...

introduction: artemisia dracunculus l. belongs to asteraceae family, and is a medicinal plant widely used in traditional medicine as a remedy for gastrointestinal disturbances. this study was undertaken to evaluate the effects of essential oil of a. dracunculus (eoad) on the rat alimentary tract. methods: the eoad was extracted by clevenger apparatus using hydrodistillation. ld50 was calculated...

In this contribution, pressurized liquid extraction (PLE) has been employed to isolate bioactive compounds from three native Romanian plants, oregano (Origanum vulgare), tarragon (Artemisia dracunculus) and wild thyme (Thymus serpyllum). Different PLE conditions have been tested including extraction with water, ethanol and their mixtures in a wide range of extraction temperatures (50-200°C), an...