the effect of clonidine, a central alpha2-adrenoreceptor agonist on reduction of anxiety, producing sedation and attenuation hemodynamic changes, were assessed during thissemi-experimental study in one of the hospitals of iran medical sciences university in tehran, 1994.   fifty surgical patients of either sex, 18-60 years of age, with asa physical status i or ii, gave informed consent to enter...

introduction: the effect of severe soft tissue injury on the severity of hemorrhagic shock is still unknown. therefore, the present study was aimed to determine hemodynamic and metabolic changes in traumatic/hemorrhagic shock in an animal model. methods: forty male rats were randomly divided into 4 equal groups including sham, hemorrhagic shock, soft tissue injury, and hemorrhagic shock + soft ...

The aim of our study was to assess whether the Finapres device is able to accurately monitor not only average blood pressure values but also blood pressure variability. To examine this issue, we analyzed 30-minute recordings of finger and intra-arterial pressure simultaneously obtained at rest in 14 patients. We compared systolic blood pressure, diastolic blood pressure, mean arterial pressure,...

Objectives To test the usefulness of continuous assessment of arterial load based on a 3-element Windkessel model by a combined analysis of the esophageal Doppler derived-blood flow and arterial pressure waveform, against standard frequency-domain analysis of arterial impedance. Methods Time-domain variables of arterial impedance were obtained by the simultaneous analysis of the Doppler derived...

OBJECTIVES Increased arterial stiffness is associated with the development of cardiovascular disease and may even predict its development at an early stage. Increased pulse pressure is seen as a marker of increased arterial stiffness and can be readily measured by ambulatory blood pressure monitoring. We propose another surrogate measure of arterial stiffness derived from ambulatory blood press...