OBJECTIVES The aim of this study was to investigate the effect of manuka honey, artificial honey and an antibacterial component (methylglyoxal) on cell division in methicillin-resistant Staphylococcus aureus (MRSA). METHODS Viability of epidemic MRSA-15 NCTC 13142 incubated with manuka honey, artificial honey and methylglyoxal was determined, and structural effects monitored by electron micro...

Photocatalytic Nanozymes Highly active, efficient, and durable catalysts for light-driven carbon dioxide water conversion to fuels are pivotal a sustainable energy cycle. In article number 2207380, Philip M. Stanley, Julien Warnan, Roland A. Fischer, co-workers demonstrate photocatalytic nanozyme that stems from the synergy between metal–organic framework two molecular deliver enzyme-reminiscen...

Photosynthesis consists of a series of reactions catalyzed by redox enzymes to synthesize carbohydrates using solar energy. In order to take the advantage of solar energy, many researchers have investigated artificial photosynthesis systems mimicking the natural photosynthetic enzymatic redox reactions. These redox reactions usually require cofactors, which due to their high cost become a key i...

Natural enzymes are extremely specific and efficient biocatalysts, facilitating almost every biochemical process in living organisms with rapid rate (1019 times) of reaction [1]. Although the location and function of natural enzymes are well orchestrated, their practical utility is often compromised by some of their intrinsic hitches. These drawbacks could be the high cost of production, purifi...

A series of six new tetravalent ligands (1-6) with two different sets of arms bind to the surface of β-tryptase, a tetrameric enzyme with an A(2)B(2) arrangement of its four monomers and two different binding sites on its protein surface (as suggested by a docking study). Besides proteinogenic amino acids also the guanidiniocarbonyl pyrrole cation (abbreviated as GCP), as an artificial arginine...

A novel hybrid material that mimics NAD(P)H oxidase was designed and tested for the in situ regeneration of assorted enzyme cofactors, as reported by Ana Beloqui co-workers their Communication (e202206926). This fabricated controlled assembly glucose hemin catalysts supported a functional nanogel allocates (bio)catalysts different compartments. The synthesis procedure allows fabrication heterog...

Fe-Quer Nanozymes In article number 2300261, Xianwen Wang, Zhengxuan Jiang, and co-workers successfully utilize an artificial nanoparticle drug delivery system comprising flavonoid compounds metal ions for retina natural product-based delivery. It is efficient microvascular protectant with multiple intrinsic enzyme-mimicking properties outstanding reactive oxygen species (ROS) scavenging abilit...

Reclamation of abandoned farmland is crucial to a sustainable agriculture in arid regions. This study aims to evaluate the impact of different reclamation treatments on abandoned salinized farmland. We investigated four artificial reclamation treatments, continuous cotton (CC), continuous alfalfa (CA), tree-wheat intercropping (TW) and trees (TS), which were conducted in 2011–2012 in the Manasi...

A unique artificial catalyst that mimics the structure of active sites in real enzymes using functionalized carbon nanotubes is presented. This concept will allow for the potential construction of a library of biomimetic catalysts for enzyme active centers, for which the structure-catalysis relationships are well defined.