In the prosthetic field of study simulation aspect has now been the centre of research for many years. There have also been various applications of artificial limbs in case of natural limb dis-functioning patients. But both simulation and control modeling techniques are indispensible for knowing system performance and to generate an original approach of artificial organs. An overview of the app...

Artificial valves have been used as the ultimate treatment for cardiac valvular diseases with severe morphologic and functional disorders. Currently, artificial cardiac valves are the most widely used artificial organ, but there remain problems, such as materials, opening and closing mechanisms, and distal control. The best artificial organs are considered to function in the same manner as the ...

In Artificial Life, the production of new artificial creatures always needs more and more computation power. Whereas artificial morphogenesis methods construct complete creatures using blocks, artificial embryogeny develops smaller creatures starting from a unique cell. To obtain a complete creature, organized in tissues and organs, we propose a developmental model in which cells are coded as t...

Experiments have been described in which organs cultivated in the Lindbergh apparatus have been kept alive in artificial media for periods ranging from 3 days to 3 weeks, with life continuing in portions of some glands for from 35 to 62 days. The media used varied in composition from very simple and inexpensive ones in which some serum was used to a rather complex medium containing only that ne...

3D bioprinting of tissues and organs is game changer promising technology in medicine. It has also great potential to be substitution animal models as artificial tissue or organ platforms can used for transplantation the patient directly.

regenerative medicine provides substitutes for organ transplantation, which is restricted in applicability due to immune responses against allograft and the large discrepancy between the need for organs and the number of available transplantation. an artificial environment is allowing cells to induce tissue regeneration. growth factors (gfs) play a significant role in the cell fates in their mi...

placed in an artery to keep the vessel patent to maintain blood flow. Stent implantation is a major treatment option for CAD (eg, in bypass surgery) and has saved many patients’ lives. But no therapy is without risk. In fact, in clinical practice, persistent inflammation occurs around the stent, and can result in coronary restenosis and thrombosis. Until now, however, there has not been an appr...

Do the complex processes of angiogenesis during organism development ultimately lead to a near optimal coronary vasculature in the organs of adult mammals? We examine this hypothesis using a powerful and universal method, built on physical and physiological principles, for the determination of globally energetically optimal arterial trees. The method is based on simulated annealing, and can be ...