Objetivo: verificar qual esquema de tratamento antirretroviral foi mais seguro para pessoa que vive com HIV, dolutegravir 50mg + lamivudina 300mg tenofovir ou efavirenz 600mg 300mg. Para isso, analisou-se os seguintes exames laboratoriais função hepática: bilirrubina total, direta e indireta, aspartato amino transferase, alanina gama glutamil transferase fosfatase alcalina. Metodologia: estudo ...

Chinese milk vetch (Astragalus sinicus L.) is an important leguminous green manure that frequently suffers from seasonal drought. To improve its drought tolerance, the effects of rhizobia inoculation on tolerance and underlying physiological mechanism were investigated. Drought in combination with nitrogen assimilation, free amino acids, polyamines was investigated active nodules (AN), inactive...

In a preceding paper it was shown that low concentrations of diphtheria toxin, in the presence of NAD 1 as an essential cofactor, inhibit the incorporation of amino acids into TCA-precipitable peptides in mammalian cell extracts (1). Collier (2) has demonstrated that this inhibitory action of the toxin is due to the specific inactivation of transferase II , one of the highly labile soluble enzy...

Makroalga telah digunakan industri pangan sejak lama karena komponen yang dikandungnya misalnya alginat, karagenan, dan agar. Selain itu alga mengandung nutrisi bioaktif lainnya sebagai fungsional. Kandungan protein keragaman jenis asam amino dapat menjadi informasi penting untuk memaksimalkan potensi dimiliki alga. Penelitian ini bertujuan mengetahui kandungan profil pada S.aquifolium, U. lact...

The macrolide-lincosamide-streptogramin B class (MLS) of antibiotics contains structurally different but functionally similar drugs, that all bind to the 50S ribosomal subunit. It has been suggested that these compounds block the path by which nascent peptides exit the ribosome. We have studied the mechanisms of action of four macrolides (erythromycin, josamycin, spiramycin and telithromycin), ...

A total of 540 one-day old male broilers Ross 308 were allocated to 6 treatments in a completely randomized designed with a 2×3 factorial arrangement (aflatoxin B1 (AFB1) and probiotics) with 6 replicates and 15 birds in each. Factors include aflatoxin B1 (control, 500 ppb) and probiotics (control, 108 cfu/mL Bacillus sp. MBIA2.40, 0.2 g Gallipro per kg). Results showed that adding 500 ppb AFB1...

Aminoacyl-tRNA protein transferases catalyze the transfer of amino acids from aminoacyl-tRNAs to polypeptide substrates. Different forms of these enzymes are found in the different kingdoms of life and have been identified to be central to a wide variety of cellular processes. L/F-transferase is the sole member of this class of enzyme found in Escherichia coli and catalyzes the transfer of leuc...

The kinetics of aminoacyl transfer from aminoacyl soluble ribonucleic acid to ribosomal protein has been examined with rat liver preparations. A lag in the initial rate of incorporation with resolved aminoacyl-transferring enzymes is observed with low (4 mu) concentrations of reduced glutathione; this lag is abolished when transferase II is incubated with a sulfhydryl compound, such as glutathi...

Background & Aim: Marshmallow (Althaea officinalis) is one of the most popular medicinal plants used in traditional medicine with antibacterial and antioxidant properties. This study was conducted to evaluate the effects of marshmallow extract (Althaea officinalis L.) administration on blood cells and biochemical parameters of carp liver. Experimental: 150 carp (weighing 37.6...

background: the use of devices emitted microwave radiation such as mobile phones, wireless fidelity (wi-fi) routers, etc. is increased rapidly. it has caused a great concern; the researchers should identify its effects on people's health. we evaluated the protective role of vitamin c on the metabolic and enzymatic activities of the liver after exposure to wi-fi routers. material and methods: 70...