Accepted 12 January 1996 In December 1983, a 53-year old Chinese woman presented with a one-year history of generalised pruritus. Various members of her family, extending over four generations, had autoimmunne thyroid disorders. On examination, she had bilateral xanthelasmata but no stigmata of chronic liver disease nor jaundice. Her liver was just palpable but she had neither splenomegaly nor ...

or,-Cycloserine (5 to 10 mvl), when added to isolated hepatocytes, is shown to inhibit aspartate aminotransferase predominantly in the cytosol. At low concentrations (0.1 to 0.2 mu) it selectively inhibits alanine aminotransferase. Aminooxyacetate (0.5 mu) irreversibly inhibits all transaminase activity provided the inhibitor is added prior to substrate addition. Neither cycloserine nor aminoox...

conclusions this report aimed to increase awareness of the occurrence of extra-intestinal systemic manifestations of rotavirus infection. although such cases may be rare, they still suggest that that rotavirus is a systemic viral infection. case presentations we report three pediatric cases of rotavirus infection: one accompanied by encephalopathy and two with elevated hepatic transaminase acti...

Pig heart “soluble” glutamic-aspartic transaminase (L-aspartate : 2-oxoglutarate aminotransferase, EC 2.6.1.1) will catalyze the exchange of an amino group between glutamate and ketoglutarate without the participation of any other amino acid or keto acid (1). This “exchange transamination” also occurs between aspartate and oxaloacetate. The rates of these reactions are comparable to the physiol...

Cowpea is one of the most consumed legumes in Africa. Recombinant DNA technology has been used to insert foreign genes into plants genome thereby creating a new generation with desired traits. Such possess improved seed quality, yield and resistance pests pathogens. The aim this work assess safety profile an variety cowpea by examining its effect on liver kidney.Native cowpea, IT89KD, were fed ...

Enzymes are biocatalysts and because of their remarkable properties, they are extensively used in medical diagnosis. Researches in the last two decades have concentrated more on enzymes such as creatine kinase-MB, alanine transaminase, aspartate transaminase, acid phosphatase, alkaline phosphatase etc. for clinical applications. Enzymes are the preferred markers in various disease states such a...

BACKGROUND: Dairy cows undergo physiological changes during pregnancy and lactation and cardiovascular system may alter during these periods. OBJECTIVES: Understanding the physiological effects of production periods of dairy cows on heart electrical activities can aid to better monitoring the cardiovascular system in these animals. METHODS: Five multiparous Holstein dairy cows were studied from...