background: timely diagnosis of leptospirosis is essential for early and effective treatment, for there are many differential diagnoses for it.. leptospiral researchers have an increasing interest in developing new serological methods with recombinant antigens to improve the leptospirosis diagnosis. several serological tests have been developed for the proper diagnosis of leptospirosis. objecti...

abstract background and aim: increased rate of micronucleus in buccal mucosa cells and its correlation with carcinogenesis is worth consideration. recently, occupation in dental laboratories has been proposed as a predisposing factor. therefore, the present study aimed to evaluate the effect of occupational exposure on buccal mucosa cells of dental laboratory technicians. materials and methods:...

objectives: leptin is a hormone-like protein produced by the adipose tissue. it plays an important role in protection of host against inflammation and infection. some studies have reported changes in leptin levels in the gingival crevicular fluid (gcf), saliva and blood serum of patients with periodontal disease compared to healthy individuals. the aim of the present study was to compare the sa...

objective(s): nanomaterials, especially silver nanoparticles (ag-nps), are employed in an increasing number of commercial products. this has led to an ever growing exposure of human beings to this substance. the first purpose of the nano committee of food and drug administration of the islamic republic of iran (ifda) is developing guidelines to assess and approve commercial nano-health products...

it has been reported that several members of convolvulaceae family such as convolvulus arvensis possess cytotoxic activity on some tumor cell lines. proteoglycan mixture, the water extract of c. arvensis with high molecular weight, has potent anti-angiogenesis and stimulating effects. in this study, arial parts of c. arvensis were collected and identified, and the cytotoxic effects of chlorofor...

in present study different protein measurement methods are evaluated on the allergenic extract of chenopodium album pollen, which was previously prepared in our laboratory and applied in skin prick testing in comparison with a commer¬cial extract. the protein content of similar amounts of these two extracts which had caused similar skin reactions were measured with different protein assays such...

objective(s) cigarette and nicotine enhances embryogenesis, fertility, pregnancy loss and ultrastructure alterations of oocyte. this study was performed to determine the effect of daily supplementation of vitamin e on oocytes apoptosis in nicotine-treated mice. materials and methods in this experimental study, 24 nmari adult female mice were randomly allocated into four experimental groups. for...

objective(s) comparison of prooxidant-antioxidant balance (pab) assay with crocin assay. materials and methods twenty eight serum samples were chosen, pab and the total antioxidant capacity were measured by pab assay and crocin, respectively, and the correlation of both assays, along with their correlation with other clinical and biochemical parameters, were determined. results a significant ne...

background the increasing use of herbal drugs and their ease of accessibility and availability have necessitated the use of mutagenicity test to analyze their toxicity and safety. objectives this study aimed to evaluate the genotoxicity of sankol herbal medicine in dna breakage of rat hepatocytes in comparison with h2o2 by single cell gel electrophoresis technique or comet assay. materials and ...