Early malignant syphilis is a rare and severe variant of secondary syphilis. It is clinically characterized by lesions, which can suppurate and be accompanied by systemic symptoms such as high fever, asthenia, myalgia, and torpor state. We report a diabetic patient with characteristic features of the disease showing favorable evolution of the lesions after appropriate treatment.

Marina Economou, Elias Angelopoulos, Lily E. Peppou, Kyriakos Souliotis, Costas Stefanis University Mental Health Research Institute, Athens, Greece; First Department of Psychiatry, Medical School, National and Kapodistrian University of Athens, Eginition Hospital, Athens, Greece; Faculty of Social and Political Sciences, University of Peloponnese, Corinth, Greece; Centre for Health Services Re...

BACKGROUND Outbreaks of hepatitis E frequently occur in tropical developing countries during the rainy season due to overflowing drains, short-circuiting of networks of clean water and use of contaminated water from wells. Hepatitis E virus (HEV) infections are usually accompanied by general symptoms of acute liver disease. This study was conducted to define the clinical and epidemiological asp...

PURPOSE Signaling through the fibroblast growth factor (FGF) pathway may account for tumor resistance to antiangiogenic therapies targeting the VEGF pathway. Here, dovitinib (TKI258), a potent oral inhibitor of FGF receptor, VEGF receptor (VEGFR), and platelet-derived growth factor receptor tyrosine kinases, is studied in a dose escalation trial. EXPERIMENTAL DESIGN Patients with advanced or ...

I T IS GENERALLY agreed that, prior to actual experience, less will be known concerning the effects of prolonged exposure to zero G* than about the effects of any other stress man is likely to encounter in space flight. We do know some of the effects of very short exposure. However, certain of these findings must be accepted with reservation because of the complications introduced by the experi...

The “Create” research program proposes a holistic model for learning environments that draws from experiences based on technologically saturated environments. This paper presents the first pilot experience of the research program, which implemented a one-to-one computer infrastructure in a small rural community in Costa Rica. While the majority of experiences have been done in developed countri...

We combine data from the Latin American Migration Project and the Mexican Migration Project to estimate models predicting the likelihood of taking of first and later trips to the United States from five nations: Mexico, the Dominican Republic, Costa Rica, Nicaragua, and Peru. The models test specific hypotheses about the effects of social capital on international migration and how these effects...