OBJECTIVE Exercise-induced bronchoconstriction (EIB) is defined as acute, reversible bronchoconstriction induced by physical exercise. It is widely believed that EIB occurs after exercise. However, in children with asthma the time to maximal bronchoconstriction after exercise is short, suggesting that the onset of EIB in such children occurs during exercise. AIM In this study the authors inve...

OBJECTIVE Aerobic exercise can improve cardiovascular fitness and does not seem to be detrimental to patients with asthma, though its role in changing asthma control and inflammatory profiles is unclear. The main hypothesis of the current randomised controlled trial is that aerobic exercise will be superior to usual care in improving asthma control. Key secondary outcomes are asthma quality of ...

The respiratory system rarely limits exercise in the normal subject. In patients with chronic pulmonary processes or in the elite athlete, however, the respiratory system may indeed be the limiting factor. Common respiratory disorders include chest pain syndromes, cough, exercise-induced asthma, and vocal cord dysfunction. Chronic lung diseases such as asthma, COPD, and interstitial lung diseas...

To investigate the mechanisms contributing to refractoriness in exercise induced asthma a methacholine challenge test was performed 30 minutes before and 30 minutes after two exercise tests 45 minutes apart. Exercise was performed by 12 asthmatic patients while they were breathing cold air. There was a smaller airway response to the second exercise test than to the first, though there was wide ...

PURPOSE To estimate the sensitivities, specificities, and predictive values of exercise challenge and questionnaire, when these tests are used to diagnose asthma in children. METHODS Participants were children, predominantly aged 6 to 12 years, selected from three primary school grades among 18 different schools in Montreal. Of 1111 participants, 989 successfully completed a six-minute free r...

Exercise-induced bronchospasm (EIB) is acute and reversible airway narrowing that occurs during, and also frequently after, exercise. Because the presenting symptoms of EIB are nonspecific, objective evidence of bronchospasm should be documented to confirm a diagnosis. A 10% or greater decrease in the forced expiratory volume in 1 second (FEV1) from baseline after an adequate exercise challenge...

What we know: Exercise-induced asthma (EIA) occurs in up to 23% of schoolchildren. In 40% of children with demonstrable EIA, no clinical diagnosis of asthma has been made. Children with asthma and EIA have eosinophils in their sputum, consistent with active asthma. EIA is well controlled in 50%-65% of children with moderate to severe asthma, so that only a minority will need prophylactic therap...

Abstract Background Physical effort is capable of triggering airway obstruction in asthmatics, the so-called exercise-induced bronchoconstriction asthma (EIBa). This study was performed subjects with mild persistent asthma, aiming to find predictors for developing EIBa. Methods In 20 measurements baseline functional respiratory parameters and airways responsiveness by a methacholine challenge w...

BACKGROUND Little is known about the effect of exposure to air pollution during exercise or time spent outdoors on the development of asthma. We investigated the relation between newly-diagnosed asthma and team sports in a cohort of children exposed to different concentrations and mixtures of air pollutants. METHODS 3535 children with no history of asthma were recruited from schools in 12 com...