BACKGROUND Patient history gives important clues about the likelihood of atopy. However, the accuracy of assessment of atopy based on detailed allergy history is low. The objective of this survey was to determine the successful prediction rate of atopy by a questionnaire and the effect of various factors on the successful prediction. METHODS A standard questionnaire including detailed allergy...

Macrophage migration inhibitory factor (MIF) is a pleiotrophic lymphocyte and macrophage cytokine; it is likely to play an important role in innate immunity. Genome-wide search for atopy susceptibility genes recently identified human chromosome 22q11, where the gene encoding MIF resides, as a region of interest for atopic traits. Both the -173G/C and -794 [CATT]5-8 repeat polymorphisms in the M...

PURPOSE OF REVIEW Both atopy and diseases from the spectrum of dermatitis and eczema are among the most frequent clinical problems worldwide; nevertheless, they are still poorly defined and too frequently misdiagnosed. In the present review, studies pertinent to this topic were systematized and critically assessed with particular attention to definitions of relevant diseases. RECENT FINDINGS ...

<b><i>Introduction:</i></b> Eosinophilic gastroenteritis (EoG) is a rare condition with yet poorly understood pathophysiology. <b><i>Case Presentation:</i></b> We report on case of 36-year-old woman history atopy presenting nausea, abdominal discomfort, weight loss, and ascites. Laboratorial analysis revealed peripheral eosinophilia slight elevati...

multiple sclerosis (ms) and allergy are believed to up regulate t helper cell type 1 (th1) and t helper cell type 2 (th2) responses, respectively. it has been shown that disequilibrium in the  ratio  of  th1/th2  activities may increase frequency of  one  disease and  decrease the frequency of the other. the aim of this study was to investigate the relation of ms with allergy and atopy in new d...

BACKGROUND The pathogenesis of COPD is complex and remains poorly understood. The European Respiratory Society Study on Chronic Obstructive Pulmonary Disease (EUROSCOP) investigated long-term effects of budesonide; 18% of the COPD participants were atopic. So far effects of atopy on the long-term course of COPD have not been elucidated. METHODS Factors related to the presence of atopy (positi...