The anatomy of the ostium primum atrial septal defect has been known since Rokitansky's description in 1875. However, until the introduction of cardiac catheterization and open heart surgery, information about the physiology and clinical features of this condition lagged behind knowledge of the morbid anatomy. Attempts at surgical correction have influenced the natural history, and information ...

Abnormal systolic interventricular septal motion is an echocardiographic manifestation of right ventricular volume overload. In order to determine the anatomical basis for this echocardiographic finding, septal motion recorded by left lateral or left anterior oblique ventriculograms was compared with echocardiography ventricular septal motion. Thirteen patients with secundum atrial septal defec...

BACKGROUND Recent advances in diagnosis and treatment have increased the life expectancy of patients with congenital heart disease. METHODS To investigate the prevalence of adult congenital heart disease (ACHD) in a large registry of patients over a 20-year period, we retrospectively assessed data of 14,012 males and 4,461 females who underwent clinically indicated cardiac catheterization fro...

The authors report a case of double-orifice mitral valve (DOMV) which showed mitral stenosis and mild insufficiency. An associated anomaly was secundum atrial septal defect. DOMV is an unusual congenital heart defect. The occurrence of this anomaly with or without secundum atrial septal defect is very rare. More often it is associated with other congenital malformations arising from atrioventri...

Hypoplastic left heart syndrome (HLHS) comprises 2 to 3 percent of all congenital heart disease. HLHS is uniformly lethal if left untreated; however, there is currently an estimated 70 percent 5-year survival rate for infants who undergo surgical correction. The hypoplastic left heart syndrome encompasses a spectrum of cardiac malformations that are characterized by significant underdevelopment...

BACKGROUND Secundum atrial septal defect is a common congenital heart disease. Amplatzer septal occluder has become the most commonly used device for its closure. This study was conducted to determine the safety and outcome of atrial septal defect closure with the Amplatzer septal occlude (ASO). METHODS This Case-series was conducted at Armed Forces Institute of Cardiology/National Institute ...

Atrial Septal Defect (ASD) is one of the most frequently congenital heart diseases in adults and it is often asymptomatic until adulthood. We report a case of a 90-year-old woman admitted to hospital with dyspnea and orthopnea insidiously progressing over the preceding 5 years and becoming severe with dyspnea on minimal activities, orthopnea and paroxysmal nocturnal dyspnea, in the last 2 weeks...

5 List of papers 7 Abbreviations 7 Introduction 8 Embryology 8 Genetics 10 Anatomy of the atrial septum 10 Classifications of shunt lesions at the atrial level 11 Incidence of atrial septal defect 13 Haemodynamics 15 Quantification of shunts – methodological aspects 19 Natural history 24 Clinical presentation 25 Atrial septal defect and pulmonary hypertension 26 Atrial septal defect and atrial ...

Abstract Background A higher prevalence of congenital heart defects (CHD) in neuroblastoma patients in general population is reported in some publications, however, some authors did not find such an association. The evidence for this relation comes from the observation that, the neural crest cells accompany to the development of the heart and neuroblastoma as well. Materials and Methods We...