A 15-year-old male, no relevant medical history, was admitted after a 5 day episode of epigastric pain together with referred pain in the back. Denial of toxic habits. Having received antibiotic treatment for tonsillitis days before his admission. A physical examination revealed the presence of a right occipital adenopathy and bilateral inguinal lymphadenopathy, as well as erythematous pharynx ...

We report a rare case of isolated unilateral acute retinal necrosis syndrome without any history of associated herpes zoster or other conditions attributed to HIV infection as the initial manifestation of HIV infection. A 30-year-old man presented with a history of sudden diminished vision in the right eye with no apparent predisposing factors. Examination revealed right eye acute retinal necro...

Two patients with "pure akinesia" who showed the characteristic changes of progressive supranuclear palsy (PSP) at necropsy are described. They had akinesia but no rigidity or tremor, and ophthalmoplegia was not observed during the course of illness. The symptoms of "pure akinesia" was not improved by levodopa therapy but was considerably improved by L-threo-3,4-dihydroxy-phenylserine. At necro...

Parathyroid carcinoma is an extremely rare endocrine malignancy that accounts for less than 1% of cases of primary hyperparathyroidism. We report a 44-year-old woman who presented with fatigue and diffuse bone pain. Laboratory findings revealed highly elevated serum calcium and parathyroid hormone (PTH) levels and a 4.5 × 3 × 2.5 cm cystic lesion in the lower pole of the right thyroid lobe that...

chigger fever, is a mite-transmitted zoonosis caused by Orientia tsutsugamushi. The vector is the larval stage (chigger) of the trombiculid mite (Leptotrombidium deliense and several other Leptotrombidium spp). The mites and the rodents that carry them serve as the major reservoirs1. Scrub typhus is widely prevalent in the ‘tsutsugamushi triangle’ region of the world spanning the Indian subcont...

Papulo- and vesiculo-necrotic lesions are rare manifestations of secondary syphilis. Until now it has been described only in HIV-infected patients with advanced stages of immunosuppression. This case report describes an unusual case of PLEVA-like syphilis in a 33-year-old man with newly diagnosed HIV infection. Despite that the CD4 cells level and viral load did not indicate the advance stage o...

We present a rare manifestation of common pathology: Left sided sensorineural hearing loss secondary to subclavian steal syndrome (SSS) after thoracic endovascular aortic repair (TEVAR) for complicated acute dissection [Figure 1]. describe the vascular physiology that may result in unilateral and provide brief review SSS. This case report highlights importance avid clinical recognition an atypi...

Reticulohistiocytoma (RH) is a dermal histiocytic infiltration composed of large histiocytes with eosinophilic glassy cytoplasm. RH is classified into three clinical forms: solitary RH, diffuse cutaneous RH without systemic involvement and multicentric reticulohistiocytosis with systemic diseases. Solitary RH generally manifests as a nodular lesion in adults without accompanying systemic diseas...

Atypical manifestation of Huntington's disease (HD) could inform ongoing research into HD genetic modifiers not present in the primarily European populations studied to date. This work demonstrates that expanding HD genetic testing into under-resourced healthcare settings can benefit both local communities and ongoing research into HD etiology and new therapies.

We report what is to our knowledge the first case of severe isolated vertigo that developed after renal transplantation and was a manifestation of cryptococcal meningitis. Treatment with antifungal therapy resulted in the complete resolution of vertiginous symptoms. Immunosuppressed patients with an opportunistic infection of the central nervous system can present with extremely tenuous feature...