As many as 59% of the transcription factors in Escherichia coli regulate the transcription rate of their own genes. This suggests that auto-regulation has one or more important functions. Here, one possible function is studied. Often the transcription rate of an auto-regulator is also controlled by additional transcription factors. In these cases, the way the expression of the auto-regulator re...

We report a study that examines performance of pilots flying a simulated UAV in a highfidelity environment while using different types of perfect and imperfect automation aids. Fiftysix student pilots carried out simulated UAV missions containing a 3D view of terrain, a 2D topdown navigational map, system parameter gauges, and a message box. Trajectory and manipulation of a 3D camera was contro...

Introduction Auto-inflammatory syndromes are defined as conditions caused by an exaggerated innate immune system response, resulting in episodes of spontaneous inflammation affecting multiple organs. The prototypical auto-inflammatory disorders are associated with periodic febrile episodes. Auto-inflammatory syndromes now include polygenic diseases, such as Behcet’s syndrome and Still’s disease...