نتایج جستجو برای: bace 1

تعداد نتایج: 2752751  

Journal: :BMC complementary and alternative medicine 2016
Xue Wang Karuppasamy Sankarapandian Yizhe Cheng Soon Ok Woo Hyung Wook Kwon Haribalan Perumalsamy Young-Joon Ahn

BACKGROUND Propolis (or bee glue), collected from botanical sources by honey bee, has been used as a popular natural remedies in folk medicine throughout the world. This study was conducted to assess growth inhibitory effects of ethanol extracts of propolis (EEPs) from 20 different regions in South Korea on human intestinal bacteria as well as their human β-amyloid precursor cleavage enzyme (BA...

Journal: :Alzheimers & Dementia 2023

Background Alzheimer’s Disease (AD), the most common cause of dementia, is characterized by amyloid plaques accumulation, generated after APP cleavage enzymes, being important beta-secretase-1 (BACE1) (Hardy and Selkoe, 2002). Small-molecule BACE1 inhibitors reduced production amyloid-β peptide, but clinical trials have demonstrated some adverse effects, although non-progressive reversible, whi...

2018
Jona Kurpiers Daniel M. Balazs Andreas Paulke Steve Albrecht Ilja Lange Loredana Protesescu Maksym V. Kovalenko Maria Antonietta Loi Dieter Neher

Time Delayed Collection Field (TDCF) and Bias Assisted Charge Extraction (BACE) experiments are used to investigate the charge carrier dynamics in PbS colloidal quantum dot solar cells. We find that free charge carrier creation is slightly field dependent, thus providing an upper limit to the fill factor. BACE measurements reveal a rather high effective mobility of 2 × 10 cm2/Vs, meaning that c...

Journal: :Nature Reviews Drug Discovery 2016

Journal: :Geological Society of America Bulletin 2022

The Ediacaran−Cambrian boundary strata in the Great Basin of southwestern United States record biological, geochemical, and tectonic change during transformative interval Earth history which metazoans diversified. Here, we integrate new compiled chemostratigraphic, paleontological, sedimentological, stratigraphic data sets from Death Valley region, White-Inyo Ranges, Esmeralda County Nevada Cal...

2011
Jantine Scheele Pim AJ Luijsterburg Manuela L Ferreira Chris G Maher Leani Pereira Wilco C Peul Maurits W van Tulder Arthur M Bohnen Marjolein Y Berger Sita MA Bierma-Zeinstra Bart W Koes

BACKGROUND Although back complaints are common among older people, limited information is available in the literature about the clinical course of back pain in older people and the identification of older persons at risk for the transition from acute back complaints to chronic back pain. The aim of this study is to assess the course of back complaints and identify prognostic factors for the tra...

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