background: acute bacterial meningitis is among serious infections of the central nervous system (cns). the early diagnosis and empiric antibiotic treatments have led to a reduction in morbidity and mortality rates. pcr and the enzymatic digestion of 16s rdna fragment following the pcr by universal primers led up fast and sensitive determination. the aims of the present study was to improve our...

Pythium myriotylum is a notorious soil-borne oomycete that causes post-emergence damping-off in chili pepper. Of various disease management strategies, utilization of plant growth promoting rhizobacteria (PGPR) suppression and promotion an interesting strategy. The present study was performed to isolate characterize PGPR indigenous the rhizosphere Pakistan, test potential suppress chili. Out to...

fire blight is an important worldwide disease of pome fruits that control of which through antibiotics is particularly critical. in this case and in absence of another chemical methods, the biocontrol methods can be considered as the best alternative for control of fire blight. in this study efficacy of 5 isolates of antagonistic bacteria belongs to pseudomonas fluorescens and pantoea agglomera...

The potential of bacterial antagonists of fungal pathogens to control the root-knot nematode Meloidogyne incognita was investigated under greenhouse conditions. Treatment of tomato seeds with several strains significantly reduced the numbers of galls and egg masses compared with the untreated control. Best performed Bacillus subtilis isolates Sb4-23, Mc5-Re2, and Mc2-Re2, which were further stu...

The global rise of anti-microbial resistance, combined with the rapid rate of microbial evolution, and the slower development of novel antibiotics, underscores the urgent need for innovative therapeutics. We are facing a post-antibiotic era with a decreased armamentarium to combat infectious diseases. Development of novel drugs will rely on basic research aimed to increase our understanding of ...

Chemical fungicides viz. propiconazole, thiram, bayleton, copper-oxy-chloride, benomyl and mancozeb in three different concentrations were screened for their fungicidal efficacy against P. pinnata seed mycoflora viz., Penicillium sp., A. oryzae, A. ustus, A. sydowii, A. fumigatus, A. flavus, A. niger, Rhizopus sp., Fusarium sp., C. gloeosporioides and Absidia sp. in in-vitro conditions by poiso...

Phytophthora agathidicida is a highly virulent pathogen of kauri (Agathis australis) and the causal agent dieback disease in New Zealand’s forests. This study aimed to identify microbial isolates isolated from forest soils that inhibited growth P. agathidicida. Three different forms vitro bioassays were used assess inhibition each isolate on mycelial Furthermore, head space (HS) solid-phase mic...

All forms of cerebral inflammation as found in bacterial meningitis, cerebral malaria, brain injury, and subarachnoid haemorrhage have been associated with vasospasm of cerebral arteries and arterioles. Vasospasm has been associated with permanent neurological deficits and death in subarachnoid haemorrhage and bacterial meningitis. Increased levels of interleukin-1 may be involved in vasospasm ...

Many receptors undergo ligand-induced conformational changes to initiate signal transduction. Periplasmic binding proteins (PBPs) are bacterial receptors that exhibit dramatic conformational changes upon ligand binding. These proteins mediate a wide variety of fundamental processes including transport, chemotaxis, and quorum sensing. Despite the importance of these receptors, no PBP antagonists...