We performed a meta-analysis of 10 randomized trials of 5,066 patients with 6 to 12 months of follow-up. The summary risk differences excluded any major differences between the 2 types of stents for death (0.12%, 95% confidence interval [CI] -0.34% to 0.58%, p = 0.60) and overall myocardial infarction (0.04%, 95% CI -0.72% to 0.81%, p = 0.91). There was a modest increase in the risk of Q-wave m...

c s c u r r d t m t p s p a t l t a B b w d a t a 0 d S o s rug-eluting stents have been the most successful strategy or the prevention of restenosis after percutaneous coronary nterventions (1). In line with this, the STRATEGY Single High-Dose Bolus Tirofiban and Sirolimus Eluting tent versus Abciximab and Bare Metal Stent in Acute yocardial Infarction) study showed a marked decrease in he nee...

BACKGROUND Concerns about the long-term safety of drug-eluting stents (DES) in saphenous vein grafts has become an area of controversy and uncertainty. METHODS AND RESULTS In this retrospective registry, we compared the outcomes in 127 patients (143 lesions) treated with DES from April 2002 to June 2006 (DES group) with 131 patients (160 lesions) treated with bare-metal stents in the precedin...

The development of stent has been a major achievement in treating obstructive coronary artery disease (OCAD). The main obstacle in the long term success of percutaneous coronary intervention (PCI) was the neo-intimal hyperplasia developed within the stent, which may leads to instent restenosis. The introduction of Drug-eluting stents (DES) shows steep decrease in angiographic restenosis when co...

A 60-year-old man with a history of implantation of two bare-metal stents 2 years prior presented to the emergency department with new-onset chest pain. He has been regularly taking angiotensinconverting enzyme inhibitors, beta blockers and aspirin. Aspirin was suspended for 10 days prior to the current hospitalization in order to perform surgery to remove a kidney tumor. He underwent coronary ...

Percutaneous coronary interventions (PCIs) are standard therapy for the treatment of atherosclerotic lesions of the coronary arteries. Since the introduction of rotational atherectomy (RA) in 1989, it has become established as a necessary adjunct to PCI in a small proportion of cases, notably calcified lesions. However, its use is hampered by the recurrent phenomenon of restenosis. The introduc...

The prospective multicenter German Drug-Eluting Stent (DES.DE) registry is an observational study to analyze and evaluate the therapeutic principle of the differential drug-eluting stents (sirolimus- and paclitaxel-eluting stents) and bare metal stents under real world conditions in the context of the German healthcare system. The baseline clinical and angiographic characteristics and follow-up...

Aortic coarctation is a correctable hypertensive disease. For safety reasons and due to the invasiveness of surgical techniques, percutaneous interventions have become drastically more popular in recent times. In elderly patients with aortic coarctation who are at risk of an aortic wall aneurysm and rupture, covered stents are preferred but in younger patients, bare metal stenting may be suffic...

In a 27 months period from Aug. 2010 to October 2012, 189 patients (aged 35-79, mean 56.6 years, 169 males) with 318 stents subsequently underwent ICA after CTA on the same day in 182 (96.3%) patients, on the second day in 6 (3.2%), and on the 4th day in one patient (0.5%). The interval time between the last stents implantation and CTA was 3.6 to 61.6 (mean 11.2) months. Significant ISR was def...

The bare metal stent (BMS) used in the blood vessel caused the restenosis after the operation due to formation and proliferation of neointimal. Recently, as a method to overcome the problems of BMS, drug eluting stent (DES) is developed and being applied to human body which has drug reducing restenosis applied on the metal surface. DES has the advantage of greatly reducing the restenosis after ...