Results The index case was a 10 year old Afro-Caribbean boy who initially presented with a non-progressive developmental delay and severe chilblains (the chilblains improved with methotrexate). He developed transient acute ataxia and flattened affect, with visual and auditory hallucinations. Parotid swelling, arthritis and proximal myopathy were noted, but autoantibodies were negative and compl...

INTRODUCTION Fahr's disease is characterized by bilateral calcium deposition within the basal ganglia, cerebellar dentate nucleus and subcortical brain white matter. The main clinical manifestations are rigid or hyperkinetic syndrome, mood disorders and cognitive impairment. The correlation between neurological impairment and symmetrical basal ganglia calcification is not so frequent. Aim of th...

Familial idiopathic basal ganglia calcification: rediscovering an old challenge in organic psychiatric disorders João Ricardo Mendes de Oliveira, Matheus Fernandes de Oliveira Keizo Asami Laboratory (LIKA), Universidade Federal de Pernambuco (UFPE), Recife, PE, Brazil. Neuropsychiatric Department, UFPE, Recife, PE, Brazil. Neurosurgery Residency Program, Hospital do Servidor Público Estadual de...

Stenosis of a DVA may result in chronic venous ischemia. We present 6 patients (3 men, 3 women; age range, 30-79 years; mean age, 53 years) with unilateral calcification of the caudate and putamen on noncontrast CT. This calcification typically spared the anterior limb of the internal capsule. No patient presented with symptoms referable to the basal ganglia or had an underlying metabolic disor...