Take home messages The majority of basal-like breast cancers have a triple negative phenotype and the vast majority of triple negative cancers display a basal-like transcriptome, however the two are not synonymous. Basal-like and triple negative breast cancers comprise a heterogeneous group of diseases, which are characterised by a constellation of morphological features. Not all basal-like and...

malignancies of the midface result in cosmetic deformities that make maxillofacial prosthesis as an integral part of the treatment plan. facial defects can be devastating in their impact on physical structure and function of the affected individual, leading to potentional compromises in quality of life. reconstruction of nasal defects is a challenge for the prosthodontist because of esthetic an...

objective: basal cell carcinoma (bcc) is the most common human malignant neoplasm which is more frequent in white individuals. ptch and p53 are two major tumor suppressor genes which play important roles in pathogenesis of bcc. ptch is a twelve-pass transmembrane protein. it is an essential component of the sonic hedgehog signaling pathway that plays as a receiving receptor for members of the h...

Background and Objectives: Alternative treatment approaches to basal cell carcinoma (BCC) are necessary in inoperable BCC.

Basal cell carcinoma is the most common skin cancer, characterised by a slow growing behavior, metastasis are extremely rare, and it occurs in less than 0, 1% of all cases. Giant basal cell carcinoma is a rare form of basal cell carcinoma, more aggressive and defined as a tumor measuring more than 5 cm at its largest diameter. Only 1% of all basal cell carcinoma develops to a giant basal cell c...

Background: Surgery is the most frequent treatment modality for basal cell carcinoma but in spite of its high cure rate, the frequency of incomplete excision varies widely (0.7-50%) among dermatologic centers. Our case series was designed to determine the frequency of incompletely excised basal cell carcinoma and the related risk factors. Methods: A total of 1424 basal cell carcinoma (1040 pati...