the objective of this research was to investigate the influence of the over-expression of recombinant interferon-g during high cell density cultivation on cellular characteristics of recombinant e. coli. batch and fed-batch culture techniques were employed to grow escherichia coli bl21 for production of human gamma-interferon in pet expression system. final cell densities in batch and fed-batch...

We consider the problem of minimizing the makespan(Cmax) on m identical parallel batch processing machines. The batch processing machine can process up to B jobs simultaneously. The jobs that are processed together form a batch, and all jobs in a batch start and complete at the same time. For a batch of jobs, the processing time of the batch is equal to the largest processing time among the job...

We develop an automated wavelet-based spectral method for constructing an approximate confidence interval on the steady-state mean of a simulation output process. This procedure, called WASSP, determines a batch size and a warmup period beyond which the computed batch means form an approximately stationary Gaussian process. Based on the log-smoothed-periodogram of the batch means, WASSP uses wa...

An integrated strategy for the tracking control of product qualities in batch processes is proposed by combing batch-to-batch iterative learning control (ILC) with on-line shrinking horizon model predictive control (SHMPC) within a batch. ILC is used in batch-to-batch control and the convergence of batch-wise tracking error under ILC is guaranteed. On-line SHMPC within a batch can reduce the ef...

Scheduling is a key factor for manufacturing productivity. Effective scheduling can improve on-time delivery, reduce work-in-process inventory, cut lead time, and improve machine utilization. Motivated by the extensive use of batch machines in manufacturing industries, the scheduling of job shops with batch machines is studied in this paper. Unlike machines that can process one part at a time (...

Abstract This paper presents the results of research on analysis historical data from a vision system developed by authors, installed inside glass furnace in one packaging glassworks. In particular, authors focused batch blanket asymmetry coefficient and line position tank. The information obtained allows to see phenomena occurring that were previously difficult notice. Based this, recommendati...

Optimal control has wide applications for the control of batch and semi-batch processes to develop an optimum control input policy by extremizing a performance measure. The deployment of optimal control relies heavily on the accuracy of the process models being used for computation of the optimal profile. Often, the process models do not replicate the plants due to various shortcomings such as ...

The objective of this research was to investigate the influence of the over-expression of recombinant interferon-g during high cell density cultivation on cellular characteristics of recombinant E. coli. Batch and fed-batch culture techniques were employed to grow Escherichia coli BL21 for production of human gamma-interferon in pET expression system. Final cell densities in batch and fed-batch...

The prevalence of batch and batch-like operations, in conjunction with the continued resurgence artificial intelligence techniques for clustering classification applications, has increasingly motivated exploration applicability deep learning modeling feedback control processes. To this end, present study seeks to evaluate viability general, neural networks particular, toward process via a case ...

A method is proposed for batch process monitoring and fault diagnosis, starting from a single batch reference data and updating with accumulation of successive batches. A moving data window method is adopted for exploring local covariance structure, stage division, and the development of monitoring models. The application to an injection molding process shows the effectiveness and feasibility o...