BACKGROUND Cutaneous lichen planus (CLP) is an inflammatory dermatosis. Its chronic relapsing course and frequently spontaneous regression hamper the assessment of treatment effectiveness. OBJECTIVE To evaluate the efficacy of available treatment modalities for CLP. DATA SOURCES PubMed, Cochrane Central Register of Controlled Trials (CENTRAL), ClinicalTrials.gov registry. METHODS We perfo...

HINTERGRUND Primar kutane Lymphome (PCL) unterscheiden sich oft stark im klinischen Verhalten und in der Prognose von systemischen Lymphomen des gleichen histopathologischen Typs. Ziel Studie war es, die Verteilung PCL-Subtypen, Zeitspanne Krankheitsmanifestation bis zur Diagnosestellung, den Stellenwert diagnostischer Verfahren, das Auftreten Zweittumoren verschiedenen Behandlungsmodalitaten R...

BACKGROUND Limited data exist in the literature concerning the characteristics of erythema following psoralen UV-A (PUVA) treatment using topical methoxsalen. To optimize the phototherapeutic regimen and reduce short- and long-term risks, knowledge of such basic information is essential. OBSERVATIONS The characteristics of PUVA erythema following 15- and 5-minute immersion in methoxsalen was ...

BACKGROUND Smooth muscle cell proliferation plays a major role in the genesis of restenosis after angioplasty or vascular injury. Although the effects of arterial exposure to high-energy radiation sources such as laser have been investigated in detail, the effects on vascular cells of low-intensity radiant energy in combination with photoactive agents have not been extensively characterized. Ps...

Objective: Our objective is to analyze the significance of mobility of the ureterovesical junction (UVJ-M) and poster urethrovesical angle (PUVA) in diagnosing stress urinary incontinence (SUI) in women, providing a reference for clinical diagnosis of SUI. Methods: A total of 90 female SUI patients admitted in our hospital between January, 2015-January, 2016 were selected as observation group, ...

BACKGROUND Multimodality biological response-modifier therapy that includes photopheresis, interferon, and bexarotene is the standard of care in our institution for advanced cutaneous T-cell lymphoma with peripheral blood involvement. We added psoralen plus long-wave UV-A (PUVA) to this regimen in 5 patients with Sézary syndrome. OBSERVATIONS All patients responded with decreased Sézary count...

The transcapillary escape rate of albumin (TERalb), i.e., the fraction of intravascular albumin mass passing to the extravascular space per unit time, is a parameter of the leakage of macromolecules from the total microvasculature. In patients with psoriasis short-term PUVA treatment induces an increase in TERalb. In this study TERalb was measured in 3 groups of normal humans treated with PUVA,...