Alginate can be used to encapsulate mammalian cells and for the slow release of small molecules. Packaging alginate as microbead structures allows customizable delivery for tissue engineering, drug release, or contrast agents for imaging. However, state-of-the-art microbead fabrication has a limited range in achievable bead sizes, and poor control over bead placement, which may be desired to lo...

Separation of macromolecules on the basis of their molecular weight by size exclusion chromatography has long been considered to be caused by the geometry-dependent partition of macromolecules between a continuous phase and the porous interior of a gel or cross-linked bead. The volume of a pore accessible to a solute is limited by its relative dimensions, so larger molecules will have access to...

microencapsulation has become a common technique in the production of controlled release dosage forms. many results have been reported, concerning the use of alginate beads as controlled release drug formulations. alginate has a unique gel-forming property in the presence of multivalent cations, in an aqueous medium. ibuprofen is an excellent analgesic and antipyretic, non-steroidal anti-inflam...

The purpose of this study is to propose a method to decide nearoptimal settings of the welding process parameters using a genetic algorithm. This method tries to find the near-optimal settings of the welding process parameters through experiments without a model between input and output variables. It has the advantage of being able to carry out searches without modifying the design space, which...

suspension polymerization processes are significantly important in polymer bead formation. one of the important factors for bead size control in these processes is variation in surface tension. in this research, the prediction of optimum concentration of a surface active agent was investigated on the basis of the experimental surface tension diagrams. the experimental data show that the desired...

It is of interest in various scientific and industrial contexts to make a reliable estimation of the transport properties of porous media via more accessible probes such as NMR that yield information on static pore geometry and porosity. When the pore geometry is simple, there are empirical recipes that have long proven reliable in bridging the gap. For heterogeneous systems, such recipes fail ...