Propranolol controlled the rage and violent behavior of a man with alcohol withdrawal, Korsakoff's psychosis, and seizures. The authors present evidence linking Korsakoff's psychosis and alcohol withdrawal to pathophysiologic alterations in CNS adrenergic amines and receptors.

Environmental stress triggers substantial alterations in animal physiology and, in some cases, brain structure. Using the nematode Caenorhabditis elegans, a new study reports that unfavorable conditions lead to dramatic dendrite remodeling in neurons that mediate an adaptive dispersal behavior.

OBJECTIVE To review the feasibility of coupling the techniques of random amplified polymorphic DNA (RAPD) with carbon nanotube-based modified electrode for guanine/deoxyguanine triphosphate (dGTP) electrochemical sensing for mapping of the pancreatic cancer genetic fingerprint and screening of genetic alterations. METHODS We developed a new method to study the electrochemical behavior of dGTP...

Microcystins (MCs) are toxins produced by cyanobacteria (blue-green algae), primarily Microcystis aeruginosa, forming water blooms worldwide. When an organism is exposed to environmental perturbations, alterations in normal behavioral patterns occur. Behavioral repertoire represents the consequence of a diversity of physiological and biochemical alterations. In this study, we assessed behaviora...

Given the dearth of gene mutations in prostate cancer, [1] ,[2] it is likely that genomic rearrangements play a significant role in the evolution of prostate cancer. However, in the search for recurrent genomic alterations, "private alterations" have received less attention. Such alterations may provide insights into the evolution, behavior, and clinical outcome of an individual tumor. In a rec...

Cytoskeletal reorganizations, especially alterations of contractile tension generated by the actin-myosin cortex, are of central importance in the development of the phenotype of morphologically transformed neoplastic cells with invasive behavior. These reorganizations can be regarded as genetically determined aberrations of the physiological reactions of normal cells which are responsible for ...

Childhood obesity is a worldwide epidemic and public health problem. Sleep an important factor in this process, its quality duration are associated with metabolism, eating behavior, cognition, psychology. Physical activity encompasses hormonal, thermoregulatory, fatiguing, restorative processes, metabolic regulator of sleep, modestly reduces body fat through elevated energy expenditure regulati...