Divalproex is recognized as a first-line agent in the treatment of bipolar disorders (BDs) (1). However, sedation can be an unwelcome side effect of divalproex sodium treatment (2), and unwanted side effects can lead to patient noncompliance (3). Ultimately, noncompliance can contribute to hospitalizations (4). I present 2 cases in which patients treated with divalproex sodium for BD experience...

Intragastric pH was monitored during 24 hours in eight volunteers with duodenal ulcer disease in remission, while on placebo, cimetidine 400 mg bd, pirenzepine 50 mg bd, cimetidine 400 mg bd + pirenzepine 50 mg bd, cimetidine 200 mg bd + pirenzepine 25 mg bd. The control of intragastric acidity during the 24 hour period by the combination of low dose cimetidine and pirenzepine was significantly...

BACKGROUND Eosinophil cationic protein (ECP) is a matrix protein of eosinophils and has been reported to reflect eosinophil activity. Few studies have examined the role of eosinophils in the pathogenesis of Behçet's disease. OBJECTIVE The purpose of the present study was to investigate the serum ECP levels in BD and its relation to clinical activity. METHODS Forty-seven consecutive patients...

Behçet's disease (BD) is a multisystemic disorder of unknown etiology characterized by the "triple symptom complex" consisting of recurrent oral aphthosis, genital ulcers, and chronic relapsing bilateral uveitis. Recurrent mucocutaneous lesions are generally considered the hallmark of the disease, being the most common symptoms presenting at the onset of disease. Although the improvement of kno...

purpose: to analyze the clinical patterns and etiologies of uveitis in isfahan. methods: the records of 2016 patients with uveitis who had been referred to the feiz tertiary eye care center, isfahan, between 1999 and 2013 were classified and analyzed with respect to demographic, clinical, anatomical, and etiological characteristics. results: at the onset of uveitis, the mean patient age was 33....

BACKGROUND The uveo-meningeal syndromes are a group of disorders that share involvement of the uvea, retina, and meninges. REVIEW SUMMARY We review the clinical manifestations of uveitis and describe the infectious, inflammatory, and neoplastic conditions associated with the uveo-meningeal syndrome. CONCLUSIONS Inflammatory or autoimmune diseases are probably the most common clinically reco...

Behçet disease is a multisystem disease of unknown cause in which an inflammatory perivasculitis can arise in almost any tissue (Sakane et al., 1999). Neurologic involvement in Behçet disease was first reported by Knapp in 1941. It represented between 4-49% of manifestations of BD (Haghighi et al., 2005). There is one of the most serious causes of long term morbidity and mortality in Behçet’s D...