Commercial carotenoids of green microalgae have become significant especially for their applications in the cosmetic, pharmaceutical, food and feed industries. Effects physical chemical parameters on carotenoid contents isolated microalgal species been investigated. The variables shaking rate, nitrogen concentration light intensity affect biomass production synthesis were investigated using sta...

Coprecipitation-adsorption plays a significant role during coagulation-flocculation-sedimentation (C/F/S) of antimony (Sb) in water. This work uses Box–Behnken statistical experiment design (BBD) and response surface methodology (RSM) to investigate the effects major operating variables such as initial Sb(III, V) concentration (100–1000 µg/L), ferric chloride (FC) dose (5–50 mg/L), pH (4–10) on...

In the current study, corn stalk rinds were used as feedstock for production of solid-fuel pellets. an effort to comprehensively analyze effects different operational parameters on physical properties pellets, response surface methodology (RSM) was employed in conjunction with a Box–Behnken experimental design (BBD). By assessing multiple variables simultaneously and examining their interaction...

Pigeon Pea (Casanus Cajan L.) is one of the local foods in South Sulawesi. pea seeds contain protein that body can absorb. This study aims to determine optimum operating conditions for extracting pigeon on and yield using Ultrasonic-Assisted Extraction (UAE). Response Surface Methodology (RSM) with Box-Behnken Design (BBD) was used by considering three variables, time (30, 40, 50 min), temperat...

Abstract The epoxidation process of soybean oil (SBO) and peracid produced by 50 wt% hydrogen peroxide (H 2 O ) formic acid (FA) was studied with sulfuric SO 4 as a catalyst. Three reaction parameters, including temperature, FA-to-SBO ratio, H -to-SBO were investigated, along the combined effect on oxirane value (OV). Based response surface methodology (RSM), Box-Behnken design (BBD) used to op...

Biosorption is a promising alternative method to replace the existing conventional technique for Cr(VI) removal from the industrial effluent. In the present experimental design, the removal of Cr(VI) from the aqueous solution was studied by Aspergillus niger MSR4 under different environmental conditions in the batch systems. The optimum conditions of biosorption were determined by investigating...

BACKGROUND Recombinant human endostatin (rhES) is an angiogenesis inhibitor used as a specific drug for the treatment of non-small-cell lung cancer. As mRNA concentration affects the recombinant protein expression level, any factor affecting mRNA concentration can alter the protein expression level. Response surface methodology (RSM) based on the Box-Behnken design (BBD) is a statistical tool f...

Gloriosa superba is a medicinal plant used in traditional medicine for the treatment of various diseases. The tuber of Gloriosa superba is a rich source of colchicine which is used for the treatment of gout, cirrhosis and also used in plant breeding studies to produce polyploidy. Optimization of various extraction parameters using response surface methodology (RSM) was performed to assess maxim...

The culture conditions for the yield of a polysaccharide (PCPS) produced by Paecilomyces cicadae (Miquel) Samson on solid-state fermentation were investigated using response surface methodology (RSM). Plackett-Burman design (PBD) was applied to screen out significant factors, followed by the paths of steepest ascent to move to the nearest region of maximum response. Then Box-Behnken design (BBD...

Various modeling techniques were used to understand fluidized bed granulation using a two-step approach. First, Plackett-Burman design (PBD) was used to identify the high-risk factors. Then, Box-Behnken design (BBD) was used to analyze and optimize those high-risk factors. The relationship between the high-risk input variables (inlet air temperature X1, binder solution rate X3, and binder-to-po...