The present study combines the theory and the experimental data to predict the changes on intestinal bacterial populations during ingestion of beneficial probiotic bacteria. Our proposed model is a modified version of the LotkaVolterra model, which takes the probiotic administration into account. Using the linear stability analysis of the model, the conditions for coexistence of the probiotics ...

Previously, we demonstrated that Propionibacterium acnes, a human skin commensal bacterium, ferments glycerol into short-chain fatty acids, including propionic acid. Propionic acid suppressed the growth of Staphylococcus aureus USA300, a community-acquired methicillin-resistant bacterium, in vitro and in vivo. In this study, it is demonstrated that the anti-USA300 activity of propionic acid per...

Acne vulgaris has long been postulated to feature a gastrointestinal mechanism, dating back 80 years to dermatologists John H. Stokes and Donald M. Pillsbury. They hypothesised that emotional states (e.g. depression and anxiety) could alter normal intestinal microbiota, increase intestinal permeability, and contribute to systemic inflammation. They were also among the first to propose the use o...

A field survey was conducted in Wukari, Taraba State to assess the diversity and abundance of insect species in selected habitats (residential, open field made up of grassland and an agroecosystem). Sampling were done biweekly using light, pitfall and yellow pan traps set in 3 replicates, 30 m apart. Insects recovered were wet preserved in 70% ethanol except butterflies and moths. Representativ...

Apoptosis-induced proliferation (AiP) maintains tissue homeostasis following massive stress-induced cell death. During this phenomenon, dying cells induce proliferation of the surviving cells to compensate for the tissue loss, and thus restore organ size. Along with wound healing and tissue regeneration, AiP also contributes to tumor repopulation following radiation or chemotherapy. There are s...

To make food resources accessible, provide supplemental nutrition and fend off parasites, animals, including humans, often rely on symbiotic microorganisms (Dethlefsen et al. 2007; Rosenberg et al. 2007; Klepzig et al. 2009). In contrast, many microbes, such as filamentous fungi or bacteria, render food sources unpalatable to animals (Janzen 1977; Burkepile et al. 2006; Rozen et al. 2008). Inse...

Mutualisms, beneficial interactions between species, are expected to be unstable because delivery of benefit likely involves fitness costs and selection should favour partners that deliver less benefit. Yet, mutualisms are common and persistent, even in the largely promiscuous associations between plants and soil microorganisms such as arbuscular mycorrhizal fungi. In two different systems, we ...

Methicillin-resistant Staphylococcus aureus (MRSA) is a pathogen of major public health importance. Colonisation precedes infection; thus reducing MRSA carriage may be of benefit for reducing infection. Probiotics represent a novel approach to reducing MRSA carriage. We undertook a pilot feasibility randomised controlled trial of the tolerability and acceptability of probiotics for reducing nas...

The effects of diets supplemented with either chickpea or its main oligosaccharide raffinose on the composition of the faecal microbial community were examined in 12 healthy adults (18-65 years) in a randomised crossover intervention study. Subjects consumed their usual diet supplemented with soups and desserts that were unfortified, or fortified with either 200 g/d of canned chickpeas or 5 g/d...