Previous studies have demonstrated that tides are subject to considerable changes on secular time scales. However, these rely sea level observations from tide gauges predominantly located in coastal and shelf regions therefore, the large-scale patterns remain uncertain. Now, for first time, satellite radar altimetry (TOPEX/Poseidon & Jason series) has been used study worldwide linear trends tid...

The axial component of the oceanic tidal angular momentum (OTAM) has been demonstrated tobe responsible for most of the diurnal and semidiurnal variations in Earth's rotational rate. In this paper we study the equatorial components of OTAM and their corresponding effects on the orientation of Earth's rotational axis, or polar motion. Three ocean tide models derived from TOPEX/Poseidon satellite...

The Yermak Plateau (YP), located northwest of Svalbard in Fram Strait, is the final passage for the inflow of warm Atlantic Water into the Arctic Ocean. The region is characterized by the largest barotropic tidal velocities in the Arctic Ocean. Internal response to the tidal flow over this topographic feature locally contributes to mixing that removes heat from the Atlantic Water. Here, we inve...

The 3 April 2017 Mw 6.5 Moiyabana earthquake (Central Botswana) had a significant impact on groundwater levels; gradual co-seismic increase and stepwise decline in levels were observed response to the at boreholes MH2 Z12836, respectively. In this study, we investigated of Earth tides by computing amplitude phase shift M2 tidal constituent estimate temporal variations storativity, transmissivit...

It is generally believed that plasma membrane glycoconjugates influence corneal epithelial cell migration after wounding. Previous studies have focused on the role of glycoproteins in this event. The present study was designed to determine whether migration-specific glycolipids are synthesized by epithelium of healing rabbit corneas. Migrating and nonmigrating rabbit corneal epithelia were incu...

Tides have been recognized as a major driving forcing affecting coastal aquifer system, and deterministic modeling has been very effective in elucidating mechanisms caused by tides. However, such modeling does not lend itself to capture embedded information in the signal, and rather focuses on the primary processes. Here, using yearlong data sets measured at beaches in Alaska Prince William Sou...

Alternatively activated (M2) macrophages play critical roles in diverse chronic diseases, including parasite infections, cancer, and allergic responses. However, little is known about the acquisition and maintenance of their phenotype. We report that M2-macrophage marker genes are epigenetically regulated by reciprocal changes in histone H3 lysine-4 (H3K4) and histone H3 lysine-27 (H3K27) methy...

Tumor cell metabolism is characterized by abundant glucose consumption and aerobic glycolysis. And pyruvate kinase M2 (PKM2) plays a decisive role in glycolysis, significantly contributing to the Warburg effect, tumor growth, angiogenesis, cell division, metastasis and apoptosis. To date, researchers have unraveled the potential of pyruvate kinase M2 as an antitumor target, which suggests a new...