BACKGROUND AND OBJECTIVES We compared the estimations of Cockcroft-Gault, Modification of Diet in Renal Disease (MDRD), and Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equations to a gold standard GFR measurement using (125)I-iothalamate, within strata of GFR, gender, age, body weight, and body mass index (BMI). DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS For people who prev...

Recall bias has been given considerable attention in textbooks and methodological research because of its potential to jeopardize the validity of epidemiologic results. Case-control studies on self-reported ultraviolet radiation exposure as a risk factor for melanoma have been described as especially prone to the deleterious effect of recall bias because of the growing public awareness about th...

Utilizing multiple biomarkers is increasingly common in epidemiology. However, the combined impact of correlated exposure measurement error, unmeasured confounding, interaction, and limits of detection (LODs) on inference for multiple biomarkers is unknown. We conducted data-driven simulations evaluating bias from correlated measurement error with varying reliability coefficients (R), odds rati...

Utilizing multiple biomarkers is increasingly common in epidemiology. However, the combined impact of correlated exposure measurement error, unmeasured confounding, interaction, and limits of detection (LODs) on inference for multiple biomarkers is unknown. We conducted data-driven simulations evaluating bias from correlated measurement error with varying reliability coefficients (R), odds rati...

management to make decisions that are clinically justified and economically prudent. Epidemiology is concerned primarily with the distribution and determinants of the frequency of disease in populations.1 Thanks in large part to epidemiology, the middle of the 20th century saw many great advances in public health, such as the Framingham Heart Study,2 identifying the association between cigarett...

Public Health]. Selvmord i Danmark—Markant fald i selvmord, menstigende antal selvmordsfprsøge, Hvorfor? [Suicide in Denmark—a decrease in suicide completion but a increase in suicide attempt, why?] København: Kailow Graphic A/S, 2005 (in Danish). 10 Greenland S, Lash TL, Rothman KJ. Concepts of interaction. In: Rothman KJ, Greenland S, Lash TL (eds). Modern Epidemiology. 3rd edn. Philadelphia,...