Recent advances in the use of GC coupled to MS have allowed a chemically guided isolation of uncommon and bioactive alkaloids. The present study was aimed to focus on the extraction and screening of alkaloids from Epipremnum aureum (Linden and Andre) Bunting. It has been observed that the plant is very rich in alkaloids and the modified method employed for the extraction of alkaloid is efficien...

Evodiamine, a naturally occurring indole alkaloid, is one of the main bioactive ingredients of Evodiae fructus. With respect to the pharmacological actions of evodiamine, more attention has been paid to beneficial effects in insults involving cancer, obesity, nociception, inflammation, cardiovascular diseases, Alzheimer's disease, infectious diseases and thermo-regulative effects. Evodiamine ha...

The invasive green alga Caulerpa cylindracea has become an important component of the diet of the Mediterranean white seabream Diplodus sargus. As a consequence of this "exotic diet", the algal bisindolic alkaloid caulerpin accumulates in the fish tissues. Although the compound shows structural similarity to endogenous indolamines that modulate animal behaviour, the potential impact of caulerpi...

Actinomycetes are prolific producers of pharmacologically important compounds accounting for about 70% of the naturally derived antibiotics that are currently in clinical use. In this study, we report on the isolation of Streptomyces sp. strains from Mediterranean sponges, on their secondary metabolite production and on their screening for anti-infective activities. Bioassay-guided isolation an...

The present investigations were aimed to evaluate the antimicrobial and antioxidant efficacies of budmunchiamine-A (BUA) of Albizia amara . The activity-guided isolation leaded to isolate the bioactive compound budmunchiamine-A from alkaloid extract of A. amara . The budmunchiamine-A showed significant broad-spectrum antimicrobial activity with zone of inhibition (ZOI), minimum inhibitory conce...

Centrifugated extract of endophytic Pseudomonas azotoformans strain UICC B-91 has been observed for its antimicrobial activity against Escherichia coli ATCC 8739, Bacillus cereus 10876, Staphylococcus aureus 6583, 25923, Salmonella typhimurium 25241, aeruginosa 15442, subtilis 19659 and Candida albicans 10231, with minimum concentration in the range 250 μg/mL. But, novel compound bioactive subs...

Halimeda sp is a green seaweed belonging to the order Bryopsidales, class Chlorophyta. Production data from genus in Indonesia yet has not been reported by Ministry of Fisheries and Marine Affairs because it belonged unknown type potential. The purpose this study was determine chemical bioactive components seaweed. included moisture content, ash, protein, fat, carbohydrates (by different). Anal...

Caffeine is a naturally occurring alkaloid found in various plants. It acts as stimulant, antioxidant, anti-inflammatory, and even an aid pain management, several over-the-counter medications. This derived bioactive compound the best-known ingredient coffee other beverages, such tea, soft drinks, energy widely consumed worldwide. Therefore, it extremely important to research effects of this sub...

Seven Sungkai Peronemins compounds belong to the alkaloid group, Peronemin A2, A3, B1, B2, B3, C1, and D1. contains several bioactive compounds, triterpenoids, alkaloids, flavonoids, phenolics, steroids, saponins which can act as anti-inflammatory candidates. Geometry optimization find most stable molecular structure SMILES of peronemin compound was used predict pIC50 using pChEMBL® program. Fr...

In recent years, more and attention has been given to the naturally occurring alkaloids due their unique bioactive properties. particular, 1-Deoxynojirimycin (DNJ), an iminosugar derivative, attracting growing as anti-diabetic, anti-obesity, anti-microbial, anti-cancer, cardioprotective agent. This alkaloid is detected in various parts of mulberry plant, such leaves, latex, root bark. The predo...