ÐOngoing research is reported aimed at improving bio®xation through the use of bioactive glass coatings on Ti-based implant alloys. The optimized processing conditions for coating with one promising bioactive glass composition are discussed, and the stress corrosion crack growth behavior in a simulated human physiological environment is presented. This glass can be successfully used to coat Ti ...

Submit Manuscript | http://medcraveonline.com only osteoconductivity but also osteoinductivity, has attracted much interests in the field of bone tissue engineering but not only. Indeed, the typical silicate bioactive glasses demonstrated to bond to bone more efficiently than any other synthetic materials [1]. However, it was rapidly found that the highly disrupted silica network of bioactive g...

-The bioactive glass 45S5 (Hench glass), having composition 45 SiO2 24.5 Na2O 24.5 CaO -6 P2O5 (wt %) were prepared with substituted Li2O, K2O, ZnO, MgO, and B2O3 by conventional melting process in an electric globar furnace at 1400±10 OC. The Controlled crystallization were carried out to convert the bioglasses to their corresponding bioglass ceramics. Nucleation and crystallization regimes we...

It is extremely difficult to realize two conflicting properties-high hardness and toughness-in one material. Nano-polycrystalline stishovite, recently synthesized from Earth-abundant silica glass, proved to be a super-hard, ultra-tough material, which could provide sustainable supply of high-performance ceramics. Our quantum molecular dynamics simulations show that stishovite amorphizes rapidly...

The effects of bioactive glass S53P4 or beta-tricalcium phosphate; and bone morphogenetic proteins bone morphogenetic protein-2, bone morphogenetic protein-7, or bone morphogenetic protein-2 + 7 on osteogenic differentiation of human adipose stem cells were compared in control medium, osteogenic medium, and bone morphogenetic protein-supplemented osteogenic medium to assess suitability for bone...

Received: 17 December 2006 Accepted: 1 August 2007 Abstract: Objective: Bioactive glass is often used as a filler material for repair of dental bone defects. In different studies osteogenic potential of this material was proved, but its dentinogenesis property is in doubt. The purpose of this study was to evaluate the histological pulp responses of Calcium hydroxide and Bioactive glass placed d...

Bioactive glass is composed mainly of silica, sodium oxide, calcium oxide and phosphates. The bone-bonding reaction results from a series of reactions in the glass and its surface (Hench & Wilson, 1984). When granules of bioactive glass are inserted into bone defects, ions are released in body fluids and precipitate into a bone-like apatite on the surface, promoting the adhesion and proliferati...

The cytotoxicity of the biomaterials is a key issue that should be addressed prior to pre-clinical applications. This study was designed to evaluate and compare the cytotoxixity of two forms of bioactive glasses:nanopowder:andmicropowder. Human HGF1-PI53 gingival fibroblast cells were used to evaluate the cytotoxicity of 0.5, 1, 1.5, 2, 5, 10, 15 and 20 mg/mL concentrations of the two bioactive...

Bioactive glass has been demonstrated as a biocompatible bone substitute. However bone healing process can be prolonged due to late resorption of the material. Adipose derived stem cells (ASC) have osteogenic differentiation potential and hence can be a cell source for bone regeneration. The aim of this study was to test whether combination of bioactive glass with ASCs would enhance bone regene...